PDLIM7 PDZ and LIM domain 7 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PDLIM7provided by VGNC
Official Full Name: PDZ and LIM domain 7provided by VGNC
Primary source: VGNC:VGNC:75848
See related: Ensembl:ENSMMUG00000003146
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	6	NC_041759.1 (174977682..174991776, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	6	NC_027898.1 (176140654..176154159, complement)

Chromosome 6 - NC_041759.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH65364 (e-PCR)
- UniSTS:26687

SHGC-148959 (e-PCR)
- UniSTS:176705

PDLIM7_8917 (e-PCR)
- UniSTS:471708

STS_03 (e-PCR)
- UniSTS:257014

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables muscle alpha-actinin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heart development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in muscle structure development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in Z disc	IEA Inferred from Electronic Annotation more info	PubMed
located_in adherens junction	IEA Inferred from Electronic Annotation more info	PubMed
part_of filamentous actin	IEA Inferred from Electronic Annotation more info	PubMed
located_in stress fiber	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: PDZ and LIM domain protein 7

Names: PDZ and LIM domain 7 (enigma)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041759.1 Reference Mmul_10 Primary Assembly

Range

174977682..174991776 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015141524.2 → XP_014997010.1 PDZ and LIM domain protein 7 isoform X4

UniProtKB/TrEMBL

G7MUG3

Conserved Domains (6) summary

cd09452
Location:248 → 299

LIM1_Enigma; The first LIM domain of Enigma

cd09456
Location:307 → 358

LIM2_Enigma; The second LIM domain of Enigma

cd09458
Location:366 → 420

LIM3_Enigma; The third LIM domain of Enigma

PHA03247
Location:83 → 221

PHA03247; large tegument protein UL36; Provisional

cd00992
Location:5 → 79

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:103 → 154

DUF4749; Domain of unknown function (DUF4749)
XM_028849958.1 → XP_028705791.1 PDZ and LIM domain protein 7 isoform X2

UniProtKB/TrEMBL

F7EPE5, G7MUG3, I0FWE5

Related

ENSMMUP00000004210.4, ENSMMUT00000004461.4

Conserved Domains (6) summary

cd09452
Location:282 → 333

LIM1_Enigma; The first LIM domain of Enigma

cd09456
Location:341 → 392

LIM2_Enigma; The second LIM domain of Enigma

cd09458
Location:400 → 454

LIM3_Enigma; The third LIM domain of Enigma

PHA03247
Location:81 → 247

PHA03247; large tegument protein UL36; Provisional

cd00992
Location:5 → 79

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:130 → 188

DUF4749; Domain of unknown function (DUF4749)
XM_028849957.1 → XP_028705790.1 PDZ and LIM domain protein 7 isoform X1

UniProtKB/TrEMBL

G7MUG3

Conserved Domains (6) summary

cd09452
Location:289 → 340

LIM1_Enigma; The first LIM domain of Enigma

cd09456
Location:348 → 399

LIM2_Enigma; The second LIM domain of Enigma

cd09458
Location:407 → 461

LIM3_Enigma; The third LIM domain of Enigma

PHA03247
Location:97 → 262

PHA03247; large tegument protein UL36; Provisional

cd00992
Location:5 → 79

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:136 → 195

DUF4749; Domain of unknown function (DUF4749)
XM_028849959.1 → XP_028705792.1 PDZ and LIM domain protein 7 isoform X3

UniProtKB/TrEMBL

G7MUG3

Conserved Domains (5) summary

PHA03377
Location:35 → 201

PHA03377; EBNA-3C; Provisional

cd09452
Location:258 → 309

LIM1_Enigma; The first LIM domain of Enigma

cd09456
Location:317 → 368

LIM2_Enigma; The second LIM domain of Enigma

cd09458
Location:376 → 430

LIM3_Enigma; The third LIM domain of Enigma

cd00992
Location:5 → 79

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
XM_015141526.2 → XP_014997012.1 PDZ and LIM domain protein 7 isoform X5

Conserved Domains (4) summary

cd09456
Location:255 → 306

LIM2_Enigma; The second LIM domain of Enigma

cd09458
Location:314 → 368

LIM3_Enigma; The third LIM domain of Enigma

pfam15936
Location:51 → 95

DUF4749; Domain of unknown function (DUF4749)

cl02475
Location:196 → 247

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
XM_028849960.1 → XP_028705793.1 PDZ and LIM domain protein 7 isoform X6

UniProtKB/TrEMBL

F7EPD7, I0FWE6

Related

ENSMMUP00000004211.4, ENSMMUT00000004462.4

Conserved Domains (2) summary

cd00992
Location:5 → 79

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:130 → 188

DUF4749; Domain of unknown function (DUF4749)