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    PLA2G2E phospholipase A2 group IIE [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704299, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PLA2G2Eprovided by VGNC
    Official Full Name
    phospholipase A2 group IIEprovided by VGNC
    Primary source
    VGNC:VGNC:106473
    See related
    Ensembl:ENSMMUG00000053964
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLA2G2E in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (204809786..204813644)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (18699755..18703375, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2 group V Neighboring gene phospholipase A2 group IIA Neighboring gene OTU deubiquitinase 3 Neighboring gene ring finger protein 186

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in arachidonate secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    group IIE secretory phospholipase A2
    XP_001094364.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      204809786..204813644
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001094364.2 → XP_001094364.1  group IIE secretory phospholipase A2

      See identical proteins and their annotated locations for XP_001094364.1

      UniProtKB/TrEMBL
      A0A5F8AEH8
      Related
      ENSMMUP00000075366.1, ENSMMUT00000093656.1
      Conserved Domains (1) summary
      cd00125
      Location:20 → 135
      PLA2c; Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a metal-dependent ...
    Nucleotide Protein
    Heading Accession and Version

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