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    MUL1 mitochondrial E3 ubiquitin protein ligase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705429, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MUL1provided by VGNC
    Official Full Name
    mitochondrial E3 ubiquitin protein ligase 1provided by VGNC
    Primary source
    VGNC:VGNC:106413
    See related
    Ensembl:ENSMMUG00000051774
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MUL1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (204219619..204228947)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (19294323..19304405, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E type 3-like Neighboring gene 40S ribosomal protein S4-like Neighboring gene family with sequence similarity 43 member B Neighboring gene uncharacterized LOC114673958 Neighboring gene calcium/calmodulin dependent protein kinase II inhibitor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in organelle organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial ubiquitin ligase activator of NFKB 1
    Names
    mitochondrial E3 ubiquitin ligase 1
    NP_001248584.1
    XP_014984494.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261655.1 → NP_001248584.1  mitochondrial ubiquitin ligase activator of NFKB 1

      See identical proteins and their annotated locations for NP_001248584.1

      Status: PROVISIONAL

      Source sequence(s)
      JV044957
      UniProtKB/TrEMBL
      A0A5F7ZY44, F7EZL0
      Related
      ENSMMUP00000069716.1, ENSMMUT00000089451.1
      Conserved Domains (3) summary
      COG5574
      Location:260 → 341
      PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      pfam12483
      Location:97 → 251
      GIDE; E3 Ubiquitin ligase
      cd16648
      Location:301 → 340
      mRING-HC-C3HC5_MAPL; Modified RING finger, HC subclass (C3HC5-type), found in mitochondrial-anchored protein ligase (MAPL) and similar proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      204219619..204228947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015129008.2 → XP_014984494.1  mitochondrial ubiquitin ligase activator of NFKB 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZY44
      Conserved Domains (3) summary
      COG5574
      Location:224 → 305
      PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      pfam12483
      Location:61 → 215
      GIDE; E3 Ubiquitin ligase
      cd16648
      Location:265 → 304
      mRING-HC-C3HC5_MAPL; Modified RING finger, HC subclass (C3HC5-type), found in mitochondrial-anchored protein ligase (MAPL) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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