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    FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696396, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FDFT1provided by VGNC
    Official Full Name
    farnesyl-diphosphate farnesyltransferase 1provided by VGNC
    Primary source
    VGNC:VGNC:72631
    Locus tag
    EGK_18680
    See related
    Ensembl:ENSMMUG00000054351
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FDFT1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (8738123..8772578, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (7894412..7929184, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene cathepsin B Neighboring gene activated RNA polymerase II transcriptional coactivator p15 pseudogene Neighboring gene nei like DNA glycosylase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables squalene synthase [NAD(P)H] activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in farnesyl diphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    squalene synthase
    NP_001247653.1
    XP_015000223.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260724.1 → NP_001247653.1  squalene synthase

      See identical proteins and their annotated locations for NP_001247653.1

      Status: PROVISIONAL

      Source sequence(s)
      JV046458
      UniProtKB/TrEMBL
      A0A1D5QYJ8, A0A8J8YAZ6, G7N0H3, H9EUN1
      Related
      ENSMMUP00000053129.2, ENSMMUT00000063140.2
      Conserved Domains (1) summary
      TIGR01559
      Location:38 → 370
      squal_synth; farnesyl-diphosphate farnesyltransferase

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      8738123..8772578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144737.2 → XP_015000223.1  squalene synthase isoform X1

      UniProtKB/TrEMBL
      A0A5F7Z7X6
      Related
      ENSMMUP00000061600.1, ENSMMUT00000085153.1
      Conserved Domains (1) summary
      TIGR01559
      Location:89 → 421
      squal_synth; farnesyl-diphosphate farnesyltransferase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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