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    CASP12 caspase 12 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 724039, updated on 9-Nov-2023

    Summary

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    Gene symbol
    CASP12
    Gene description
    caspase 12
    See related
    Ensembl:ENSMMUG00000016548
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    Caspase-12
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    Genomic context

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    See CASP12 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (98145701..98161551, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (97780804..97795622, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene platelet derived growth factor D Neighboring gene DNA damage inducible 1 homolog 1 Neighboring gene uncharacterized LOC106993453 Neighboring gene caspase 4 Neighboring gene caspase 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Saleh M, et al. Nature, 2004 May 6. PMID 15129283
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    caspase-12
    Names
    CASP-12
    NP_001035896.1
    XP_028688716.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042431.2 → NP_001035896.1  caspase-12

      See identical proteins and their annotated locations for NP_001035896.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ644576
      UniProtKB/Swiss-Prot
      Q153Z0
      UniProtKB/TrEMBL
      A0A5F8AFY8
      Related
      ENSMMUP00000057591.2, ENSMMUT00000055572.2
      Conserved Domains (2) summary
      smart00115
      Location:168 → 419
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
      cd08325
      Location:6 → 88
      CARD_CASP1-like; Caspase activation and recruitment domain found in Caspase-1 and related proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      98145701..98161551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832883.1 → XP_028688716.1  caspase-12 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RBA0, A0A5F8AFY8
      Related
      ENSMMUP00000076832.1, ENSMMUT00000082067.1
      Conserved Domains (2) summary
      smart00115
      Location:168 → 419
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
      cd08325
      Location:6 → 88
      CARD_CASP1-like; Caspase activation and recruitment domain found in Caspase-1 and related proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q153Z0.1 GenPept UniProtKB/Swiss-Prot:Q153Z0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials