LOC718859 Fc fragment of IgG receptor and transporter [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: LOC718859
Gene description: Fc fragment of IgG receptor and transporter
Locus tag: EGK_10892
See related: Ensembl:ENSMMUG00000063172
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: FCGRT
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Genomic context

Location:: chromosome: 19

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	19 Unlocalized Scaffold	NW_021160363.1 (22694..38307)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	19	NC_027911.1 (44907384..44924029)

NW_021160363.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Both pIgR and FcRn mRNA levels were significantly reduced in the duodenal mucosa during acute SHIV infection and in the jejunum and caecum during chronic SHIV/SIV infection.
Title: Alteration of Polymeric Immunoglobulin Receptor and Neonatal Fc Receptor Expression in the Gut Mucosa of Immunodeficiency Virus-Infected Rhesus Macaques.
polymorphisms of neonatal Fc receptor in rhesus macaques
Title: Polymorphisms of neonatal Fc receptor in cynomolgus and rhesus macaques.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables beta-2-microglobulin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: IgG receptor FcRn large subunit p51

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001257520.1 → NP_001244449.1 IgG receptor FcRn large subunit p51 precursor

See identical proteins and their annotated locations for NP_001244449.1

Status: PROVISIONAL

Source sequence(s)

JU322969

UniProtKB/TrEMBL

A0A8J8XLZ4, G7NLP1, H9Z6D2, I0FJX2

Related

ENSMMUP00000078324.1, ENSMMUT00000091087.1

Conserved Domains (2) summary

cd21011
Location:198 → 290

IgC1_MHC-like_FcRn; immunoglobulin domain of neonatal Fc receptor, major histocompatibility complex (MHC)-like; member of the C1-set of Ig superfamily (IgSF) domains

cl08246
Location:25 → 197

MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2