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    GFPT1 glutamine--fructose-6-phosphate transaminase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574376, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GFPT1provided by VGNC
    Official Full Name
    glutamine--fructose-6-phosphate transaminase 1provided by VGNC
    Primary source
    VGNC:VGNC:72915
    See related
    Ensembl:ENSMMUG00000013797
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GFPT1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (39412276..39480449)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (70361787..70426848, complement)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene AP2 associated kinase 1 Neighboring gene small nucleolar RNA SNORA36 family Neighboring gene NFU1 iron-sulfur cluster scaffold Neighboring gene ANTXR cell adhesion molecule 1 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L7a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elevated gene expression levels distinguish human from non-human primate brains. Cáceres M, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557539, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables carbohydrate derivative binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in UDP-N-acetylglucosamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in carbohydrate derivative biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein N-linked glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    Names
    glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
    NP_001252836.1
    XP_014967953.2
    XP_014967955.2
    XP_014967956.2
    XP_014967957.1
    XP_014967958.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265907.1 → NP_001252836.1  glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

      See identical proteins and their annotated locations for NP_001252836.1

      Status: PROVISIONAL

      Source sequence(s)
      JV046749
      UniProtKB/TrEMBL
      F6TDC4, H9FSX2
      Conserved Domains (1) summary
      PLN02981
      Location:1 → 681
      PLN02981; glucosamine:fructose-6-phosphate aminotransferase

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      39412276..39480449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015112467.2 → XP_014967953.2  glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AI34
      Related
      ENSMMUP00000077565.1, ENSMMUT00000090260.1
      Conserved Domains (1) summary
      PLN02981
      Location:121 → 817
      PLN02981; glucosamine:fructose-6-phosphate aminotransferase

    2. XM_015112469.2 → XP_014967955.2  glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZAT0, A0A5F8AI34
      Related
      ENSMMUP00000062289.1, ENSMMUT00000090459.1
      Conserved Domains (1) summary
      PLN02981
      Location:121 → 799
      PLN02981; glucosamine:fructose-6-phosphate aminotransferase

    3. XM_015112470.2 → XP_014967956.2  glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AI34, A0A5F8AJW1
      Related
      ENSMMUP00000078131.1, ENSMMUT00000079932.1
      Conserved Domains (1) summary
      PLN02981
      Location:96 → 791
      PLN02981; glucosamine:fructose-6-phosphate aminotransferase

    4. XM_015112472.2 → XP_014967958.1  glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X5

      UniProtKB/TrEMBL
      A0A5F7ZJA8, F6TDC4
      Related
      ENSMMUP00000064722.1, ENSMMUT00000092430.1
      Conserved Domains (1) summary
      PLN02981
      Location:1 → 699
      PLN02981; glucosamine:fructose-6-phosphate aminotransferase

    5. XM_015112471.2 → XP_014967957.1  glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X4

      UniProtKB/TrEMBL
      F6TDC4
      Related
      ENSMMUP00000018147.4, ENSMMUT00000019377.4
      Conserved Domains (4) summary
      PLN02981
      Location:29 → 725
      PLN02981; glucosamine:fructose-6-phosphate aminotransferase
      cd00714
      Location:29 → 328
      GFAT; Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In ...
      cd05008
      Location:412 → 537
      SIS_GlmS_GlmD_1; SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal ...
      cd05009
      Location:569 → 723
      SIS_GlmS_GlmD_2; SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal ...
    Nucleotide Protein
    Heading Accession and Version

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