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    ITGAV integrin subunit alpha V [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707756, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITGAVprovided by VGNC
    Official Full Name
    integrin subunit alpha Vprovided by VGNC
    Primary source
    VGNC:VGNC:73783
    See related
    Ensembl:ENSMMUG00000019462
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITGAV in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (73697763..73788623)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (73883140..73975776)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106992658 Neighboring gene zinc finger CCCH-type containing 15 Neighboring gene uncharacterized LOC106992659 Neighboring gene family with sequence similarity 171 member B Neighboring gene zinc finger SWIM-type containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin alpha-V
    Names
    integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265953.1 → NP_001252882.1  integrin alpha-V precursor

      See identical proteins and their annotated locations for NP_001252882.1

      Status: PROVISIONAL

      Source sequence(s)
      JU472963
      UniProtKB/TrEMBL
      A0A1D5RJA5, F6QSK2, H9ETF2
      Related
      ENSMMUP00000060399.2, ENSMMUT00000072541.2
      Conserved Domains (4) summary
      smart00191
      Location:367 → 421
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:467 → 914
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:221 → 271
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
      sd00039
      Location:51 → 120
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      73697763..73788623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110495.2 → XP_014965981.1  integrin alpha-V isoform X1

      UniProtKB/TrEMBL
      F6QSK2
      Conserved Domains (4) summary
      smart00191
      Location:366 → 420
      Int_alpha; Integrin alpha (beta-propellor repeats)
      pfam08441
      Location:466 → 913
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:220 → 270
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
      sd00039
      Location:51 → 120
      7WD40; WD40 repeat [structural motif]

    2. XM_028830544.1 → XP_028686377.1  integrin alpha-V isoform X2

      UniProtKB/TrEMBL
      F6QSK2
      Conserved Domains (4) summary
      smart00191
      Location:185 → 239
      Int_alpha; Integrin alpha (beta-propellor repeats)
      sd00039
      Location:72 → 116
      7WD40; WD40 repeat [structural motif]
      pfam08441
      Location:285 → 732
      Integrin_alpha2; Integrin alpha
      pfam13517
      Location:39 → 89
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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