U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ERBB3 erb-b2 receptor tyrosine kinase 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711407, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ERBB3provided by VGNC
    Official Full Name
    erb-b2 receptor tyrosine kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:108514
    See related
    Ensembl:ENSMMUG00000020758
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ERBB3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (55640936..55662914)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (54815164..54837006)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene IKAROS family zinc finger 4 Neighboring gene uncharacterized LOC114670866 Neighboring gene ribosomal protein S26 Neighboring gene proliferation-associated 2G4 Neighboring gene ribosomal protein L41

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Widespread expression of ErbB2, ErbB3 and ErbB4 in non-human primate brain. Thompson M, et al. Brain Res, 2007 Mar 30. PMID 17280647
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neuregulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neuregulin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basal plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    receptor tyrosine-protein kinase erbB-3
    Names
    v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
    XP_015007426.2
    XP_028685437.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      55640936..55662914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151940.2 → XP_015007426.2  receptor tyrosine-protein kinase erbB-3 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QQ23, A0A663DEV3, A0A8J8YNW2, F7HL92, G7N7B1
      Related
      ENSMMUP00000050150.2, ENSMMUT00000057523.2
      Conserved Domains (5) summary
      cd05111
      Location:701 → 979
      PTK_HER3; Pseudokinase domain of the Protein Tyrosine Kinase, HER3
      cd12095
      Location:638 → 676
      TM_ErbB3; Transmembrane domain of ErbB3, a Protein Tyrosine Kinase
      pfam00757
      Location:175 → 329
      Furin-like; Furin-like cysteine rich region
      pfam14843
      Location:499 → 630
      GF_recep_IV; Growth factor receptor domain IV
      pfam01030
      Location:56 → 165
      Recep_L_domain; Receptor L domain

    2. XM_028829604.1 → XP_028685437.1  receptor tyrosine-protein kinase erbB-3 isoform X2

      UniProtKB/TrEMBL
      F7HL92
      Related
      ENSMMUP00000039441.3, ENSMMUT00000046397.3
      Conserved Domains (5) summary
      cd05111
      Location:688 → 966
      PTK_HER3; Pseudokinase domain of the Protein Tyrosine Kinase, HER3
      cd12095
      Location:625 → 663
      TM_ErbB3; Transmembrane domain of ErbB3, a Protein Tyrosine Kinase
      pfam00757
      Location:162 → 316
      Furin-like; Furin-like cysteine rich region
      pfam14843
      Location:486 → 617
      GF_recep_IV; Growth factor receptor domain IV
      pfam01030
      Location:43 → 152
      Recep_L_domain; Receptor L domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.