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    CDH8 cadherin 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708408, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CDH8provided by VGNC
    Official Full Name
    cadherin 8provided by VGNC
    Primary source
    VGNC:VGNC:70976
    Locus tag
    EGK_12850
    See related
    Ensembl:ENSMMUG00000018511
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    Cadherin-8
    Orthologs
    human mouse all
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    Genomic context

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    See CDH8 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (48832676..49230039, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (45849894..46246206, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114674364 Neighboring gene ubiquitin-conjugating enzyme E2 N-like Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC114674395

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adherens junction organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell junction assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in axon terminus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of catenin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic cleft IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cadherin-8
    Names
    cadherin-8 preproprotein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257905.1 → NP_001244834.1  cadherin-8

      See identical proteins and their annotated locations for NP_001244834.1

      Status: PROVISIONAL

      Source sequence(s)
      JU332390
      UniProtKB/TrEMBL
      A0A8J8Y887, F7A8W3, G7NPX1, H9FND6
      Related
      ENSMMUP00000024353.4, ENSMMUT00000026026.4
      Conserved Domains (3) summary
      cd11304
      Location:281 → 387
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:87 → 165
      CA; Cadherin repeats
      pfam01049
      Location:645 → 790
      Cadherin_C; Cadherin cytoplasmic region

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      48832676..49230039 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126311.2 → XP_014981797.1  cadherin-8 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QZ34, A0A1D5RCN2, F7A8W3
      Related
      ENSMMUP00000053316.2, ENSMMUT00000071366.2
      Conserved Domains (3) summary
      cd11304
      Location:281 → 387
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:87 → 165
      CA; Cadherin repeats
      pfam01049
      Location:645 → 703
      Cadherin_C; Cadherin cytoplasmic region

    2. XM_015126310.2 → XP_014981796.1  cadherin-8 isoform X1

      UniProtKB/TrEMBL
      A0A8J8Y887, F7A8W3, G7NPX1, H9FND6
      Conserved Domains (3) summary
      cd11304
      Location:281 → 387
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:87 → 165
      CA; Cadherin repeats
      pfam01049
      Location:645 → 790
      Cadherin_C; Cadherin cytoplasmic region
    Nucleotide Protein
    Heading Accession and Version

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