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    PBX1 PBX homeobox 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694416, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PBX1provided by VGNC
    Official Full Name
    PBX homeobox 1provided by VGNC
    Primary source
    VGNC:VGNC:75770
    See related
    Ensembl:ENSMMUG00000019108
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PBX1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (22042931..22373391)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (202773805..203104064, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene histone H3.3C-like Neighboring gene 60S ribosomal protein L7 pseudogene Neighboring gene microRNA mir-7177 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L35a-like Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryonic organ development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in eye development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-B-cell leukemia transcription factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      22042931..22373391
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015125589.2 → XP_014981075.1  pre-B-cell leukemia transcription factor 1 isoform X4

      Conserved Domains (2) summary
      cd00086
      Location:234 → 294
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:40 → 232
      PBC; PBC domain

    2. XM_028849923.1 → XP_028705756.1  pre-B-cell leukemia transcription factor 1 isoform X4

      Conserved Domains (2) summary
      cd00086
      Location:234 → 294
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:40 → 232
      PBC; PBC domain

    3. XM_015125575.2 → XP_014981061.1  pre-B-cell leukemia transcription factor 1 isoform X1

      UniProtKB/TrEMBL
      F6WM30, G7MF72, H9FV44
      Related
      ENSMMUP00000014901.3, ENSMMUT00000015900.4
      Conserved Domains (2) summary
      cd00086
      Location:234 → 294
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:40 → 232
      PBC; PBC domain

    4. XM_028849909.1 → XP_028705742.1  pre-B-cell leukemia transcription factor 1 isoform X1

      UniProtKB/TrEMBL
      F6WM30, G7MF72, H9FV44
      Conserved Domains (2) summary
      cd00086
      Location:234 → 294
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:40 → 232
      PBC; PBC domain

    5. XM_015125583.2 → XP_014981069.1  pre-B-cell leukemia transcription factor 1 isoform X2

      UniProtKB/TrEMBL
      G7MF72
      Conserved Domains (2) summary
      cd00086
      Location:234 → 294
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:40 → 232
      PBC; PBC domain

    6. XM_015125593.2 → XP_014981079.1  pre-B-cell leukemia transcription factor 1 isoform X4

      Conserved Domains (2) summary
      cd00086
      Location:234 → 294
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:40 → 232
      PBC; PBC domain

    7. XM_028849918.1 → XP_028705751.1  pre-B-cell leukemia transcription factor 1 isoform X3

      UniProtKB/TrEMBL
      G7MF72
      Conserved Domains (2) summary
      cd00086
      Location:205 → 265
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam03792
      Location:57 → 203
      PBC; PBC domain
    Nucleotide Protein
    Heading Accession and Version

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