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    LOC703259 chloride channel protein ClC-Ka [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703259, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC703259
    Gene description
    chloride channel protein ClC-Ka
    See related
    Ensembl:ENSMMUG00000018235
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    CLCNKA
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    Genomic context

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    See LOC703259 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (208741738..208762899, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (14956740..14964307)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene vegetative cell wall protein gp1-like Neighboring gene family with sequence similarity 131 member C Neighboring gene chloride voltage-gated channel Kb Neighboring gene heat shock protein family B (small) member 7 Neighboring gene steroid receptor associated and regulated protein Neighboring gene zinc finger and BTB domain containing 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloride transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chloride channel protein ClC-Ka
    Names
    chloride channel Ka
    chloride channel, voltage-sensitive Ka

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      208741738..208762899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028839168.1 → XP_028695001.1  chloride channel protein ClC-Ka isoform X1

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 537
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:549 → 683
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    2. XM_028839172.1 → XP_028695005.1  chloride channel protein ClC-Ka isoform X1

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 537
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:549 → 683
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    3. XM_028839186.1 → XP_028695019.1  chloride channel protein ClC-Ka isoform X5

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 534
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:546 → 672
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    4. XM_028839180.1 → XP_028695013.1  chloride channel protein ClC-Ka isoform X3

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 534
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:546 → 680
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    5. XM_028839183.1 → XP_028695016.1  chloride channel protein ClC-Ka isoform X4

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 537
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:549 → 675
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    6. XM_028839175.1 → XP_028695008.1  chloride channel protein ClC-Ka isoform X2

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 537
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:549 → 682
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    7. XM_028839190.1 → XP_028695023.1  chloride channel protein ClC-Ka isoform X6

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 469
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:529 → 623
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    8. XM_028839193.1 → XP_028695026.1  chloride channel protein ClC-Ka isoform X7

      UniProtKB/TrEMBL
      F7E038
      Conserved Domains (2) summary
      cd03683
      Location:49 → 537
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:549 → 687
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    9. XM_015120525.2 → XP_014976011.2  chloride channel protein ClC-Ka isoform X10

      UniProtKB/TrEMBL
      F7E038
      Related
      ENSMMUP00000023981.4, ENSMMUT00000025634.4
      Conserved Domains (2) summary
      cd03683
      Location:49 → 534
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
      cd04591
      Location:546 → 684
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    10. XM_028839217.1 → XP_028695050.1  chloride channel protein ClC-Ka isoform X8

      Conserved Domains (1) summary
      cd03683
      Location:49 → 469
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...

    11. XM_028839201.1 → XP_028695034.1  chloride channel protein ClC-Ka isoform X8

      Conserved Domains (1) summary
      cd03683
      Location:49 → 469
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...

    12. XM_028839208.1 → XP_028695041.1  chloride channel protein ClC-Ka isoform X8

      Conserved Domains (1) summary
      cd03683
      Location:49 → 469
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...

    13. XM_028839225.1 → XP_028695058.1  chloride channel protein ClC-Ka isoform X9

      Conserved Domains (1) summary
      cd03683
      Location:49 → 537
      ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...

    RNA

    1. XR_003724983.1 RNA Sequence

    2. XR_003724981.1 RNA Sequence

    3. XR_003724977.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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