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    NR1H3 nuclear receptor subfamily 1 group H member 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713679, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NR1H3provided by VGNC
    Official Full Name
    nuclear receptor subfamily 1 group H member 3provided by VGNC
    Primary source
    VGNC:VGNC:75505
    See related
    Ensembl:ENSMMUG00000015598
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NR1H3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (18491546..18511566, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (18757069..18778116, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene myosin binding protein C3 Neighboring gene MAP kinase activating death domain Neighboring gene DNA damage-binding protein 2-like Neighboring gene DNA damage-binding protein 2-like Neighboring gene acid phosphatase 2, lysosomal Neighboring gene protein kinase C and casein kinase substrate in neurons 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Liver x receptor modulation of gene expression leading to proluteolytic effects in primate luteal cells. Bogan RL, et al. Biol Reprod, 2012 Mar. PMID 22156476, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    oxysterols receptor LXR-alpha
    XP_014969829.1
    XP_014969830.1
    XP_014969831.1
    XP_014969832.1
    XP_014969834.1
    XP_014969835.1
    XP_014969836.1
    XP_014969837.1
    XP_014969838.1
    XP_028689300.1
    XP_028689301.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      18491546..18511566 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015114352.2 → XP_014969838.1  oxysterols receptor LXR-alpha isoform X4

      UniProtKB/TrEMBL
      F6ST28, G7NDG1
      Related
      ENSMMUP00000037144.2, ENSMMUT00000044138.3
      Conserved Domains (2) summary
      cd06954
      Location:216 → 451
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:84 → 184
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    2. XM_015114346.2 → XP_014969832.1  oxysterols receptor LXR-alpha isoform X1

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:210 → 445
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:78 → 178
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    3. XM_015114345.2 → XP_014969831.1  oxysterols receptor LXR-alpha isoform X1

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:210 → 445
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:78 → 178
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    4. XM_015114348.2 → XP_014969834.1  oxysterols receptor LXR-alpha isoform X1

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:210 → 445
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:78 → 178
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    5. XM_015114343.2 → XP_014969829.1  oxysterols receptor LXR-alpha isoform X1

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:210 → 445
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:78 → 178
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    6. XM_015114349.2 → XP_014969835.1  oxysterols receptor LXR-alpha isoform X2

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:165 → 400
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:33 → 133
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    7. XM_015114350.2 → XP_014969836.1  oxysterols receptor LXR-alpha isoform X2

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:165 → 400
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:33 → 133
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    8. XM_015114344.2 → XP_014969830.1  oxysterols receptor LXR-alpha isoform X1

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:210 → 445
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:78 → 178
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    9. XM_028833468.1 → XP_028689301.1  oxysterols receptor LXR-alpha isoform X2

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:165 → 400
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:33 → 133
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    10. XM_028833467.1 → XP_028689300.1  oxysterols receptor LXR-alpha isoform X1

      UniProtKB/TrEMBL
      G7NDG1
      Conserved Domains (2) summary
      cd06954
      Location:210 → 445
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cd07160
      Location:78 → 178
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

    11. XM_015114351.2 → XP_014969837.1  oxysterols receptor LXR-alpha isoform X3

      Conserved Domains (2) summary
      cd07160
      Location:78 → 178
      NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers
      cl11397
      Location:210 → 368
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
    Nucleotide Protein
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