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    PLCL2 phospholipase C like 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695590, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLCL2provided by VGNC
    Official Full Name
    phospholipase C like 2provided by VGNC
    Primary source
    VGNC:VGNC:76168
    See related
    Ensembl:ENSMMUG00000023775
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLCL2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (30594962..30789942, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (173539183..173733854)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene inorganic pyrophosphatase-like Neighboring gene U7 small nuclear RNA Neighboring gene TBC1 domain family member 5 Neighboring gene uncharacterized LOC114676234 Neighboring gene chromodomain Y-like protein pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GABA receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables inositol 1,4,5 trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, GABAergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inactive phospholipase C-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      30594962..30789942 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015132240.2 → XP_014987726.1  inactive phospholipase C-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A5K1V2K1, F7GVF8, I2CVE7
      Related
      ENSMMUP00000068130.1, ENSMMUT00000103404.1
      Conserved Domains (6) summary
      cd00275
      Location:753 → 881
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08597
      Location:425 → 721
      PI-PLCc_PRIP_metazoa; Catalytic domain of metazoan phospholipase C related, but catalytically inactive protein
      PLN02228
      Location:335 → 883
      PLN02228; Phosphoinositide phospholipase C
      cd13364
      Location:143 → 251
      PH_PLC_eta; Phospholipase C-eta (PLC-eta) pleckstrin homology (PH) domain
      pfam00169
      Location:145 → 251
      PH; PH domain
      pfam09279
      Location:343 → 425
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like

    2. XM_015132241.2 → XP_014987727.1  inactive phospholipase C-like protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZV56
      Conserved Domains (6) summary
      cd00275
      Location:753 → 881
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08597
      Location:425 → 721
      PI-PLCc_PRIP_metazoa; Catalytic domain of metazoan phospholipase C related, but catalytically inactive protein
      PLN02228
      Location:335 → 883
      PLN02228; Phosphoinositide phospholipase C
      cd13364
      Location:143 → 251
      PH_PLC_eta; Phospholipase C-eta (PLC-eta) pleckstrin homology (PH) domain
      pfam00169
      Location:145 → 251
      PH; PH domain
      pfam09279
      Location:343 → 425
      EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    Nucleotide Protein
    Heading Accession and Version

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