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    RB1 RB transcriptional corepressor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704871, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RB1provided by VGNC
    Official Full Name
    RB transcriptional corepressor 1provided by VGNC
    Primary source
    VGNC:VGNC:76675
    See related
    Ensembl:ENSMMUG00000007891
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RB1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (26725425..26900200)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (27468061..27644102)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114673555 Neighboring gene integral membrane protein 2B Neighboring gene PEST proteolytic signal-containing nuclear protein pseudogene Neighboring gene uncharacterized LOC114673415 Neighboring gene lysophosphatidic acid receptor 6 Neighboring gene RCC1 and BTB domain containing protein 2 Neighboring gene uncharacterized LOC106994260 Neighboring gene uncharacterized LOC106994262 Neighboring gene uncharacterized LOC114673416

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell morphogenesis involved in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron projection development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rb-E2F complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    retinoblastoma-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261047.1 → NP_001247976.1  retinoblastoma-associated protein

      See identical proteins and their annotated locations for NP_001247976.1

      Status: PROVISIONAL

      Source sequence(s)
      JU471636
      UniProtKB/TrEMBL
      A0A1D5QLD3, H9F922, I2CVJ1
      Related
      ENSMMUP00000048858.2, ENSMMUT00000055616.2
      Conserved Domains (4) summary
      pfam01857
      Location:646 → 763
      RB_B; Retinoblastoma-associated protein B domain
      pfam01858
      Location:373 → 573
      RB_A; Retinoblastoma-associated protein A domain
      pfam08934
      Location:768 → 924
      Rb_C; Rb C-terminal domain
      pfam11934
      Location:115 → 225
      DUF3452; Domain of unknown function (DUF3452)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      26725425..26900200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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