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    RGS14 regulator of G protein signaling 14 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699625, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RGS14provided by VGNC
    Official Full Name
    regulator of G protein signaling 14provided by VGNC
    Primary source
    VGNC:VGNC:76918
    See related
    Ensembl:ENSMMUG00000019807
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RGS14 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (174847198..174862388)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (176003794..176019841)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene MAX dimerization protein 3 Neighboring gene 40S ribosomal protein S20 pseudogene Neighboring gene lectin, mannose binding 2 Neighboring gene solute carrier family 34 member 1 Neighboring gene profilin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G-protein alpha-subunit binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulator of G-protein signaling 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      174847198..174862388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141511.2 → XP_014996997.2  regulator of G-protein signaling 14 isoform X1

      UniProtKB/TrEMBL
      F7G3Y7, H9FNV6
      Conserved Domains (5) summary
      cd08743
      Location:58 → 186
      RGS_RGS14; Regulator of G protein signaling (RGS) domain found in the RGS14 protein
      smart00390
      Location:524 → 546
      GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
      pfam16613
      Location:189 → 272
      RGS12_us1; Unstructured region of RGS12
      cd17137
      Location:301 → 371
      RBD1_RGS14; Ras-binding domain (RBD) 1 of regulator of G protein signaling 14 (RGS14)
      cd17139
      Location:372 → 444
      RBD2_RGS14; Ras-binding domain (RBD) 2 of regulator of G protein signaling 14 (RGS14)

    2. XM_015141512.2 → XP_014996998.2  regulator of G-protein signaling 14 isoform X2

      UniProtKB/TrEMBL
      A0A5K1VKW3, F7G3Y7, H9FNV6
      Related
      ENSMMUP00000033656.3, ENSMMUT00000040610.3
      Conserved Domains (5) summary
      cd08743
      Location:58 → 186
      RGS_RGS14; Regulator of G protein signaling (RGS) domain found in the RGS14 protein
      smart00390
      Location:498 → 520
      GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
      pfam16613
      Location:189 → 272
      RGS12_us1; Unstructured region of RGS12
      cd17137
      Location:301 → 371
      RBD1_RGS14; Ras-binding domain (RBD) 1 of regulator of G protein signaling 14 (RGS14)
      cd17139
      Location:372 → 444
      RBD2_RGS14; Ras-binding domain (RBD) 2 of regulator of G protein signaling 14 (RGS14)
    Nucleotide Protein
    Heading Accession and Version

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