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    ERCC6 ERCC excision repair 6, chromatin remodeling factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710153, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ERCC6provided by VGNC
    Official Full Name
    ERCC excision repair 6, chromatin remodeling factorprovided by VGNC
    Primary source
    VGNC:VGNC:81396
    See related
    Ensembl:ENSMMUG00000017943
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ERCC6 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (47854243..47938559)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (43537806..43619039, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene chromosome 9 C10orf53 homolog Neighboring gene choline O-acetyltransferase Neighboring gene solute carrier family 18 member A3 Neighboring gene dorsal root ganglia homeobox Neighboring gene chromosome 9 C10orf71 homolog Neighboring gene uncharacterized LOC107000122

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription-coupled nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA excision repair protein ERCC-6; chimeric ERCC6-PGBD3 protein
    Names
    excision repair cross-complementing rodent repair deficiency, complementation group 6
    XP_015002511.1
    XP_015002513.1
    XP_028682164.1
    XP_028682165.1
    XP_028682166.1
    XP_028682167.1
    XP_028682168.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      47854243..47938559
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015147027.2 → XP_015002513.1  chimeric ERCC6-PGBD3 protein isoform X5

      UniProtKB/TrEMBL
      F7EM96, H9YUI3
      Related
      ENSMMUP00000023589.4, ENSMMUT00000025213.4
      Conserved Domains (2) summary
      pfam13843
      Location:612 → 970
      DDE_Tnp_1_7; Transposase IS4
      cl00040
      Location:1022 → 1058
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

    2. XM_028826331.1 → XP_028682164.1  DNA excision repair protein ERCC-6 isoform X1

      UniProtKB/TrEMBL
      G7N1X8, H9Z691
      Conserved Domains (2) summary
      COG0553
      Location:502 → 1050
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:550 → 737
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    3. XM_015147025.2 → XP_015002511.1  DNA excision repair protein ERCC-6 isoform X2

      UniProtKB/TrEMBL
      F7EMA2, G7N1X8, H9Z691
      Related
      ENSMMUP00000023588.2, ENSMMUT00000025212.3
      Conserved Domains (3) summary
      cd00046
      Location:530 → 680
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:833 → 963
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00176
      Location:513 → 815
      SNF2_N; SNF2 family N-terminal domain

    4. XM_028826335.1 → XP_028682168.1  chimeric ERCC6-PGBD3 protein isoform X4

      UniProtKB/TrEMBL
      A0A5F8AEE0
      Related
      ENSMMUP00000076296.1, ENSMMUT00000085522.1
      Conserved Domains (2) summary
      pfam13843
      Location:652 → 1010
      DDE_Tnp_1_7; Transposase IS4
      cl00040
      Location:1062 → 1098
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

    5. XM_028826332.1 → XP_028682165.1  DNA excision repair protein ERCC-6 isoform X1

      UniProtKB/TrEMBL
      G7N1X8, H9Z691
      Conserved Domains (2) summary
      COG0553
      Location:502 → 1050
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:550 → 737
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    6. XM_028826333.1 → XP_028682166.1  DNA excision repair protein ERCC-6 isoform X1

      UniProtKB/TrEMBL
      G7N1X8, H9Z691
      Conserved Domains (2) summary
      COG0553
      Location:502 → 1050
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:550 → 737
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    7. XM_028826334.1 → XP_028682167.1  DNA excision repair protein ERCC-6 isoform X3

      UniProtKB/TrEMBL
      H9F6B7
      Conserved Domains (2) summary
      COG0553
      Location:236 → 784
      HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
      cd18000
      Location:284 → 471
      DEXHc_ERCC6; DEXH-box helicase domain of ERCC6

    RNA

    1. XR_003719302.1 RNA Sequence

      Related
      ENSMMUT00000025211.4
    Nucleotide Protein
    Heading Accession and Version

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