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    PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701969, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PFKFB1provided by VGNC
    Official Full Name
    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1provided by VGNC
    Primary source
    VGNC:VGNC:75957
    Locus tag
    EGK_20540
    See related
    Ensembl:ENSMMUG00000008425
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PFKFB1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (54672101..54725395, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (54363715..54417053, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA11 Neighboring gene MAGE family member D2 Neighboring gene trophinin Neighboring gene small nucleolar RNA SNORA11 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene 5'-aminolevulinate synthase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 6-phosphofructo-2-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fructose 2,6-bisphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      54672101..54725395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127530.2 → XP_014983016.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QA39, F6VBV5
      Related
      ENSMMUP00000011048.3, ENSMMUT00000011781.4
      Conserved Domains (3) summary
      pfam00300
      Location:231 → 414
      His_Phos_1; Histidine phosphatase superfamily (branch 1)
      pfam01591
      Location:11 → 228
      6PF2K; 6-phosphofructo-2-kinase
      pfam13671
      Location:21 → 175
      AAA_33; AAA domain

    2. XM_015127529.2 → XP_014983015.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

      UniProtKB/TrEMBL
      A0A1D5QA39
      Conserved Domains (2) summary
      pfam00300
      Location:240 → 426
      His_Phos_1; Histidine phosphatase superfamily (branch 1)
      pfam01591
      Location:38 → 237
      6PF2K; 6-phosphofructo-2-kinase

    3. XM_015127528.2 → XP_014983014.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QA39, G7NRI6
      Related
      ENSMMUP00000044907.2, ENSMMUT00000055796.2
      Conserved Domains (2) summary
      pfam01591
      Location:41 → 259
      6PF2K; 6-phosphofructo-2-kinase
      pfam00300
      Location:262 → 445
      His_Phos_1; Histidine phosphatase superfamily (branch 1)

    4. XM_028841890.1 → XP_028697723.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QA39
      Conserved Domains (2) summary
      pfam00300
      Location:262 → 439
      His_Phos_1; Histidine phosphatase superfamily (branch 1)
      pfam01591
      Location:41 → 259
      6PF2K; 6-phosphofructo-2-kinase
    Nucleotide Protein
    Heading Accession and Version

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