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    IRF8 interferon regulatory factor 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693933, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IRF8provided by VGNC
    Official Full Name
    interferon regulatory factor 8provided by VGNC
    Primary source
    VGNC:VGNC:73698
    Locus tag
    EGK_13079
    See related
    Ensembl:ENSMMUG00000008125
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IRF8 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (72926578..72949798)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (70671984..70695142)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene ER membrane protein complex subunit 8 Neighboring gene cytochrome c oxidase subunit 4I1 Neighboring gene uncharacterized LOC114674333 Neighboring gene uncharacterized LOC106995107

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon regulatory factor 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265958.1 → NP_001252887.1  interferon regulatory factor 8

      See identical proteins and their annotated locations for NP_001252887.1

      Status: PROVISIONAL

      Source sequence(s)
      JU473638
      UniProtKB/TrEMBL
      A0A5F7ZP12, A0A8J8Y1G4, F7HIN3, G7NPG2
      Related
      ENSMMUP00000010639.2, ENSMMUT00000011353.4
      Conserved Domains (2) summary
      pfam00605
      Location:9 → 113
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:203 → 381
      IRF-3; Interferon-regulatory factor 3

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      72926578..72949798
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840354.1 → XP_028696187.1  interferon regulatory factor 8 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZP12, A0A8J8Y1G4, F7HIN3, G7NPG2
      Conserved Domains (2) summary
      pfam00605
      Location:9 → 113
      IRF; Interferon regulatory factor transcription factor
      pfam10401
      Location:203 → 381
      IRF-3; Interferon-regulatory factor 3
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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