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    MMP14 matrix metallopeptidase 14 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712429, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MMP14provided by VGNC
    Official Full Name
    matrix metallopeptidase 14provided by VGNC
    Primary source
    VGNC:VGNC:74892
    Locus tag
    EGK_18005
    See related
    Ensembl:ENSMMUG00000013665
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MMP14 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (84856247..84867126)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (84164729..84176617)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999355 Neighboring gene OXA1L mitochondrial inner membrane protein Neighboring gene solute carrier family 7 member 7 Neighboring gene mitochondrial ribosomal protein L52 Neighboring gene uncharacterized LOC114679535 Neighboring gene LDL receptor related protein 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in collagen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in skeletal system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in zymogen activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    matrix metalloproteinase-14
    Names
    matrix metallopeptidase 14 (membrane-inserted)
    matrix metalloproteinase-14 preproprotein
    NP_001253739.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266810.1 → NP_001253739.1  matrix metalloproteinase-14 precursor

      See identical proteins and their annotated locations for NP_001253739.1

      Status: PROVISIONAL

      Source sequence(s)
      JV635537
      UniProtKB/TrEMBL
      A0A8J8XW88, F7GFT1, G7MX25, H9Z945
      Related
      ENSMMUP00000017968.2, ENSMMUT00000019186.4
      Conserved Domains (4) summary
      cd00094
      Location:316 → 508
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      pfam00413
      Location:118 → 284
      Peptidase_M10; Matrixin
      pfam01471
      Location:36 → 88
      PG_binding_1; Putative peptidoglycan binding domain
      pfam11857
      Location:560 → 582
      DUF3377; Domain of unknown function (DUF3377)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      84856247..84867126
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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