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    MRPS6 mitochondrial ribosomal protein S6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697852, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MRPS6provided by VGNC
    Official Full Name
    mitochondrial ribosomal protein S6provided by VGNC
    Primary source
    VGNC:VGNC:108423
    Locus tag
    EGK_13274
    See related
    Ensembl:ENSMMUG00000053087 Ensembl:ENSMMUG00000062903
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    KCNE2
    Orthologs
    human mouse all
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    Genomic context

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    See MRPS6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (12195229..12494337, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (12329390..12485405, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 34A Neighboring gene chromosome 3 C21orf140 homolog Neighboring gene small integral membrane protein 11 Neighboring gene 40S ribosomal protein S5 pseudogene Neighboring gene 40S ribosomal protein S4, X isoform-like Neighboring gene solute carrier family 5 member 3 Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene Neighboring gene uncharacterized LOC106997267

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables delayed rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables potassium channel regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small ribosomal subunit rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane repolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of delayed rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of heart rate by cardiac conduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ventricular cardiac muscle cell membrane repolarization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ventricular cardiac muscle cell action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of mitochondrial small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    potassium voltage-gated channel subfamily E member 2; 28S ribosomal protein S6, mitochondrial
    Names
    potassium voltage-gated channel subfamily E regulatory subunit 2
    potassium voltage-gated channel, Isk-related family, member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      12195229..12494337 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028845335.1 → XP_028701168.1  28S ribosomal protein S6, mitochondrial isoform X2

      Conserved Domains (2) summary
      pfam02060
      Location:156 → 219
      ISK_Channel; Slow voltage-gated potassium channel
      cl00414
      Location:1 → 38
      bS6; Bacterial ribosomal protein S6

    2. XM_015132929.2 → XP_014988415.2  28S ribosomal protein S6, mitochondrial isoform X1

      Conserved Domains (2) summary
      cd15465
      Location:3 → 67
      bS6_mito; Mitochondrial Ribosomal Protein (MRP) S6
      pfam02060
      Location:185 → 248
      ISK_Channel; Slow voltage-gated potassium channel

    3. XM_028845336.1 → XP_028701169.1  28S ribosomal protein S6, mitochondrial isoform X2

      Conserved Domains (2) summary
      pfam02060
      Location:156 → 219
      ISK_Channel; Slow voltage-gated potassium channel
      cl00414
      Location:1 → 38
      bS6; Bacterial ribosomal protein S6

    4. XM_028845337.1 → XP_028701170.1  28S ribosomal protein S6, mitochondrial isoform X2

      Conserved Domains (2) summary
      pfam02060
      Location:156 → 219
      ISK_Channel; Slow voltage-gated potassium channel
      cl00414
      Location:1 → 38
      bS6; Bacterial ribosomal protein S6

    5. XM_028845339.1 → XP_028701172.1  28S ribosomal protein S6, mitochondrial isoform X4

      Conserved Domains (1) summary
      pfam02060
      Location:115 → 178
      ISK_Channel; Slow voltage-gated potassium channel

    6. XM_028845338.1 → XP_028701171.1  28S ribosomal protein S6, mitochondrial isoform X3

      Conserved Domains (1) summary
      pfam02060
      Location:115 → 178
      ISK_Channel; Slow voltage-gated potassium channel

    7. XM_028845341.1 → XP_028701174.1  28S ribosomal protein S6, mitochondrial isoform X6

      UniProtKB/TrEMBL
      A0A5F8AGE7, F7CRE6
      Related
      ENSMMUP00000076053.1, ENSMMUT00000080882.1
      Conserved Domains (1) summary
      pfam02060
      Location:50 → 113
      ISK_Channel; Slow voltage-gated potassium channel

    8. XM_028845340.1 → XP_028701173.1  28S ribosomal protein S6, mitochondrial isoform X5

      UniProtKB/TrEMBL
      A0A5F8AGE7
      Conserved Domains (1) summary
      pfam02060
      Location:55 → 118
      ISK_Channel; Slow voltage-gated potassium channel

    9. XM_028845342.1 → XP_028701175.1  28S ribosomal protein S6, mitochondrial isoform X7

      UniProtKB/TrEMBL
      G7MMU8, H9FYL5
      Related
      ENSMMUP00000073141.1, ENSMMUT00000082465.1
      Conserved Domains (1) summary
      cd15465
      Location:3 → 96
      bS6_mito; Mitochondrial Ribosomal Protein (MRP) S6
    Nucleotide Protein
    Heading Accession and Version

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