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    FRMPD4 FERM and PDZ domain containing 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710334, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FRMPD4provided by VGNC
    Official Full Name
    FERM and PDZ domain containing 4provided by VGNC
    Primary source
    VGNC:VGNC:72802
    See related
    Ensembl:ENSMMUG00000010252
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FRMPD4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (11785046..12378475)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (11332999..11928336)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene MSL complex subunit 3 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114674890 Neighboring gene cytochrome c oxidase subunit 7C, mitochondrial-like Neighboring gene phosphoribosyl pyrophosphate synthetase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FERM and PDZ domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      11785046..12378475
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028842093.1 → XP_028697926.1  FERM and PDZ domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      G7NS90
      Conserved Domains (5) summary
      smart00295
      Location:202 → 421
      B41; Band 4.1 homologues
      cd00201
      Location:33 → 63
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:73 → 149
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:417 → 521
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:198 → 291
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)

    2. XM_028842095.1 → XP_028697928.1  FERM and PDZ domain-containing protein 4 isoform X5

      Conserved Domains (5) summary
      smart00295
      Location:202 → 421
      B41; Band 4.1 homologues
      cd00201
      Location:33 → 63
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:73 → 149
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:417 → 521
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:198 → 291
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)

    3. XM_001095042.4 → XP_001095042.2  FERM and PDZ domain-containing protein 4 isoform X4

      UniProtKB/TrEMBL
      F6QM21
      Related
      ENSMMUP00000013421.4, ENSMMUT00000014331.4
      Conserved Domains (5) summary
      smart00295
      Location:205 → 424
      B41; Band 4.1 homologues
      cd00201
      Location:36 → 66
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:76 → 152
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:420 → 524
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:201 → 294
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)

    4. XM_015126938.2 → XP_014982424.2  FERM and PDZ domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      G7NS90
      Conserved Domains (5) summary
      smart00295
      Location:205 → 424
      B41; Band 4.1 homologues
      cd00201
      Location:36 → 66
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:76 → 152
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:420 → 524
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:201 → 294
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)

    5. XM_028842094.1 → XP_028697927.1  FERM and PDZ domain-containing protein 4 isoform X3

      UniProtKB/TrEMBL
      G7NS90
      Conserved Domains (5) summary
      smart00295
      Location:205 → 386
      B41; Band 4.1 homologues
      cd00201
      Location:36 → 66
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      cd00992
      Location:76 → 152
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13183
      Location:400 → 494
      FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
      cd17170
      Location:201 → 294
      FERM_F1_FRMPD4; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM and PDZ domain-containing protein 4 (FRMPD4)
    Nucleotide Protein
    Heading Accession and Version

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