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    TLL1 tolloid like 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705831, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TLL1provided by VGNC
    Official Full Name
    tolloid like 1provided by VGNC
    Primary source
    VGNC:VGNC:78369
    See related
    Ensembl:ENSMMUG00000015799
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TLL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (163280020..163507799)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (166147128..166374895)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase TRIM38-like Neighboring gene uncharacterized LOC114678425 Neighboring gene SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 Neighboring gene annexin A10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tolloid-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      163280020..163507799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028848870.1 → XP_028704703.1  tolloid-like protein 1 isoform X2

      UniProtKB/TrEMBL
      F7GX95, G7MSA0
      Related
      ENSMMUP00000034571.3, ENSMMUT00000041543.3
      Conserved Domains (3) summary
      cd04281
      Location:99 → 298
      ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
      pfam00431
      Location:413 → 522
      CUB; CUB domain
      pfam14670
      Location:685 → 720
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    2. XM_015139468.2 → XP_014994954.1  tolloid-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QYV0, G7MSA0
      Related
      ENSMMUP00000053232.2, ENSMMUT00000078531.2
      Conserved Domains (4) summary
      cd04281
      Location:148 → 347
      ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
      pfam00431
      Location:462 → 571
      CUB; CUB domain
      pfam01400
      Location:155 → 348
      Astacin; Astacin (Peptidase family M12A)
      pfam14670
      Location:734 → 769
      FXa_inhibition; Coagulation Factor Xa inhibitory site
    Nucleotide Protein
    Heading Accession and Version

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