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    ARAF A-Raf proto-oncogene, serine/threonine kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707169, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARAFprovided by VGNC
    Official Full Name
    A-Raf proto-oncogene, serine/threonine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:69997
    See related
    Ensembl:ENSMMUG00000011418
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARAF in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (47507237..47518253)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (47750813..47761817)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 157 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene zinc finger protein 41 Neighboring gene small nucleolar RNA SNORA51 Neighboring gene uncharacterized LOC114674789 Neighboring gene synapsin I Neighboring gene TIMP metallopeptidase inhibitor 1 Neighboring gene complement factor properdin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase A-Raf
    Names
    v-raf murine sarcoma 3611 viral oncogene homolog
    XP_014982783.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      47507237..47518253
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127297.2 → XP_014982783.1  serine/threonine-protein kinase A-Raf

      UniProtKB/TrEMBL
      G7NR57, H9FU32
      Related
      ENSMMUP00000044688.1, ENSMMUT00000076266.2
      Conserved Domains (3) summary
      cd14150
      Location:309 → 573
      STKc_A-Raf; Catalytic domain of the Serine/Threonine Kinase, A-Raf (Rapidly Accelerated Fibrosarcoma) kinase
      cd17133
      Location:19 → 91
      RBD_ARAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase ARAF
      cd20870
      Location:96 → 147
      C1_A_C-Raf; protein kinase C conserved region 1 (C1 domain) found in A- and C-Raf (Rapidly Accelerated Fibrosarcoma) kinases, and similar proteins
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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