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    ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710154, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS14provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 14provided by VGNC
    Primary source
    VGNC:VGNC:69407
    See related
    Ensembl:ENSMMUG00000012330
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS14 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (67029694..67117963, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (61623774..61711893, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene putative 40S ribosomal protein S26-like 1 Neighboring gene thymus, brain and testes associated Neighboring gene uncharacterized LOC100424564 Neighboring gene perforin 1 Neighboring gene phosphatase domain containing paladin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      67029694..67117963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001107840.4 → XP_001107840.1  A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2

      UniProtKB/TrEMBL
      F7FHT3, G7N285
      Related
      ENSMMUP00000016188.4, ENSMMUT00000017284.4
      Conserved Domains (5) summary
      smart00209
      Location:555 → 607
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:273 → 457
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01562
      Location:96 → 206
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:714 → 829
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam10514
      Location:1100 → 1169
      Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD

    2. XM_015147451.2 → XP_015002937.1  A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1

      UniProtKB/TrEMBL
      G7N285
      Conserved Domains (5) summary
      smart00209
      Location:558 → 610
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:273 → 460
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01562
      Location:96 → 206
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:717 → 832
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam10514
      Location:1103 → 1172
      Bcl-2_BAD; Pro-apoptotic Bcl-2 protein, BAD
    Nucleotide Protein
    Heading Accession and Version

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