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    MADD MAP kinase activating death domain [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713613, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MADDprovided by VGNC
    Official Full Name
    MAP kinase activating death domainprovided by VGNC
    Primary source
    VGNC:VGNC:74473
    Locus tag
    EGK_06296
    See related
    Ensembl:ENSMMUG00000015602
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MADD in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (18432873..18491203, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (18698001..18756473, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 member 13 Neighboring gene Spi-1 proto-oncogene Neighboring gene myosin binding protein C3 Neighboring gene nuclear receptor subfamily 1 group H member 3 Neighboring gene DNA damage-binding protein 2-like Neighboring gene DNA damage-binding protein 2-like Neighboring gene acid phosphatase 2, lysosomal

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of Rab protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MAP kinase-activating death domain protein
    Names
    Differentially expressed in normal and neoplastic cells

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      18432873..18491203 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001107570.4 → XP_001107570.2  MAP kinase-activating death domain protein isoform X20

      UniProtKB/TrEMBL
      A0A5F8ANX9, I0FVY6
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    2. XM_028833447.1 → XP_028689280.1  MAP kinase-activating death domain protein isoform X10

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    3. XM_015114308.2 → XP_014969794.1  MAP kinase-activating death domain protein isoform X1

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    4. XM_015114340.2 → XP_014969826.1  MAP kinase-activating death domain protein isoform X30

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    5. XM_015114331.2 → XP_014969817.1  MAP kinase-activating death domain protein isoform X22

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Related
      ENSMMUP00000078783.1, ENSMMUT00000095799.1
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    6. XM_015114334.2 → XP_014969820.1  MAP kinase-activating death domain protein isoform X23

      UniProtKB/TrEMBL
      F6T6E0
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    7. XM_028833465.1 → XP_028689298.1  MAP kinase-activating death domain protein isoform X31

      UniProtKB/TrEMBL
      A0A1D5RCB9, F6T707, I2CXT5
      Related
      ENSMMUP00000020469.4, ENSMMUT00000021884.4
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    8. XM_028833466.1 → XP_028689299.1  MAP kinase-activating death domain protein isoform X32

      UniProtKB/TrEMBL
      H9G150, I2CXT4
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    9. XM_028833464.1 → XP_028689297.1  MAP kinase-activating death domain protein isoform X29

      UniProtKB/TrEMBL
      A0A1D5QXM1, I0FVY7
      Related
      ENSMMUP00000052801.2, ENSMMUT00000071257.2
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    10. XM_028833461.1 → XP_028689294.1  MAP kinase-activating death domain protein isoform X26

      UniProtKB/TrEMBL
      A0A1D5QXM1
      Related
      ENSMMUP00000057961.2, ENSMMUT00000077238.2
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    11. XM_028833452.1 → XP_028689285.1  MAP kinase-activating death domain protein isoform X15

      UniProtKB/TrEMBL
      A0A5F8ANX9, F6T6D0
      Related
      ENSMMUP00000020471.4, ENSMMUT00000021886.4
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    12. XM_028833440.1 → XP_028689273.1  MAP kinase-activating death domain protein isoform X3

      UniProtKB/TrEMBL
      A0A5F8ANX9, G7NDG0
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    13. XM_015114310.2 → XP_014969796.1  MAP kinase-activating death domain protein isoform X1

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    14. XM_028833457.1 → XP_028689290.1  MAP kinase-activating death domain protein isoform X19

      UniProtKB/TrEMBL
      A0A1D5QZY2
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    15. XM_028833463.1 → XP_028689296.1  MAP kinase-activating death domain protein isoform X28

      UniProtKB/TrEMBL
      A0A1D5QXM1
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    16. XM_028833453.1 → XP_028689286.1  MAP kinase-activating death domain protein isoform X16

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    17. XM_028833449.1 → XP_028689282.1  MAP kinase-activating death domain protein isoform X12

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    18. XM_028833443.1 → XP_028689276.1  MAP kinase-activating death domain protein isoform X6

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    19. XM_028833454.1 → XP_028689287.1  MAP kinase-activating death domain protein isoform X17

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    20. XM_028833445.1 → XP_028689278.1  MAP kinase-activating death domain protein isoform X8

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    21. XM_028833451.1 → XP_028689284.1  MAP kinase-activating death domain protein isoform X14

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    22. XM_028833450.1 → XP_028689283.1  MAP kinase-activating death domain protein isoform X13

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    23. XM_028833462.1 → XP_028689295.1  MAP kinase-activating death domain protein isoform X27

      UniProtKB/TrEMBL
      F6T6E0
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    24. XM_028833442.1 → XP_028689275.1  MAP kinase-activating death domain protein isoform X5

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    25. XM_028833448.1 → XP_028689281.1  MAP kinase-activating death domain protein isoform X11

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    26. XM_028833460.1 → XP_028689293.1  MAP kinase-activating death domain protein isoform X25

      UniProtKB/TrEMBL
      F6T6E0, F6T727, I2CUS9
      Related
      ENSMMUP00000020468.4, ENSMMUT00000021883.4
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    27. XM_028833441.1 → XP_028689274.1  MAP kinase-activating death domain protein isoform X4

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    28. XM_028833446.1 → XP_028689279.1  MAP kinase-activating death domain protein isoform X9

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    29. XM_028833439.1 → XP_028689272.1  MAP kinase-activating death domain protein isoform X2

      UniProtKB/TrEMBL
      A0A1D5RCB9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    30. XM_028833444.1 → XP_028689277.1  MAP kinase-activating death domain protein isoform X7

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    31. XM_028833458.1 → XP_028689291.1  MAP kinase-activating death domain protein isoform X21

      UniProtKB/TrEMBL
      A0A1D5QXM1
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    32. XM_015114307.2 → XP_014969793.1  MAP kinase-activating death domain protein isoform X1

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    33. XM_028833459.1 → XP_028689292.1  MAP kinase-activating death domain protein isoform X24

      UniProtKB/TrEMBL
      F6T6E0
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    34. XM_028833455.1 → XP_028689288.1  MAP kinase-activating death domain protein isoform X18

      UniProtKB/TrEMBL
      A0A5F8ANX9
      Related
      ENSMMUP00000053615.2, ENSMMUT00000067521.2
      Conserved Domains (3) summary
      smart00801
      Location:486 → 554
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:173 → 402
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:8 → 98
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    RNA

    1. XR_003722538.1 RNA Sequence

    2. XR_003722539.1 RNA Sequence

    3. XR_003722540.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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