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    MYRF myelin regulatory factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719083, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MYRFprovided by VGNC
    Official Full Name
    myelin regulatory factorprovided by VGNC
    Primary source
    VGNC:VGNC:74949
    See related
    Ensembl:ENSMMUG00000006655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    C11orf9; C14H11orf9
    Orthologs
    human mouse all
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    Genomic context

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    See MYRF in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (12386429..12423099, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (12502347..12536236, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene fatty acid desaturase 1 Neighboring gene flap structure-specific endonuclease 1 Neighboring gene microRNA mir-611 Neighboring gene diacylglycerol lipase alpha Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in central nervous system myelin maintenance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein autoprocessing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myelin regulatory factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194718.3 → NP_001181647.3  myelin regulatory factor

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000104
      UniProtKB/TrEMBL
      A0A5F7ZEW9, G7ND09
      Related
      ENSMMUP00000064133.1, ENSMMUT00000103421.1
      Conserved Domains (3) summary
      pfam05224
      Location:384 → 531
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13888
      Location:976 → 1107
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      cd10144
      Location:578 → 696
      Peptidase_S74_CIMCD; Peptidase S74 family, C-terminal intramolecular chaperone domain of Escherichia coli phage K1F endosialidase and related proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      12386429..12423099 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832869.1 → XP_028688702.1  myelin regulatory factor isoform X6

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:989 → 1120
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    2. XM_028832870.1 → XP_028688703.1  myelin regulatory factor isoform X7

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:985 → 1116
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    3. XM_028832868.1 → XP_028688701.1  myelin regulatory factor isoform X5

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:990 → 1121
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    4. XM_028832867.1 → XP_028688700.1  myelin regulatory factor isoform X4

      UniProtKB/TrEMBL
      F7H405, G7ND09
      Related
      ENSMMUP00000008748.4, ENSMMUT00000009311.4
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:1011 → 1142
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    5. XM_028832865.1 → XP_028688698.1  myelin regulatory factor isoform X2

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:1016 → 1147
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    6. XM_028832872.1 → XP_028688705.1  myelin regulatory factor isoform X9

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:928 → 1059
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    7. XM_028832866.1 → XP_028688699.1  myelin regulatory factor isoform X3

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:1012 → 1143
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    8. XM_028832864.1 → XP_028688697.1  myelin regulatory factor isoform X1

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:393 → 540
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:667 → 702
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:1017 → 1148
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:587 → 647
      Peptidase_S74; Chaperone of endosialidase

    9. XM_028832871.1 → XP_028688704.1  myelin regulatory factor isoform X8

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:305 → 452
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:579 → 614
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:929 → 1060
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:499 → 559
      Peptidase_S74; Chaperone of endosialidase

    10. XM_028832873.1 → XP_028688706.1  myelin regulatory factor isoform X10

      UniProtKB/TrEMBL
      G7ND09
      Conserved Domains (4) summary
      pfam05224
      Location:246 → 393
      NDT80_PhoG; NDT80 / PhoG like DNA-binding family
      pfam13887
      Location:520 → 555
      MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
      pfam13888
      Location:870 → 1001
      MRF_C2; Myelin gene regulatory factor C-terminal domain 2
      pfam13884
      Location:440 → 500
      Peptidase_S74; Chaperone of endosialidase
    Nucleotide Protein
    Heading Accession and Version

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