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    MTCL1 microtubule crosslinking factor 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706392, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MTCL1provided by VGNC
    Official Full Name
    microtubule crosslinking factor 1provided by VGNC
    Primary source
    VGNC:VGNC:74852
    See related
    Ensembl:ENSMMUG00000015761
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MTCL1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (69722590..69846639)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (223081..349825, complement)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene aldose reductase-like Neighboring gene uncharacterized LOC114673856 Neighboring gene RAB12, member RAS oncogene family Neighboring gene uncharacterized LOC106994414 Neighboring gene uncharacterized LOC106994413

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in microtubule bundle formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apicolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microtubule bundle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    microtubule cross-linking factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      69722590..69846639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015121546.2 → XP_014977032.2  microtubule cross-linking factor 1 isoform X9

      UniProtKB/TrEMBL
      A0A1D5QQ00
      Conserved Domains (4) summary
      COG1196
      Location:792 → 938
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:1 → 317
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:162 → 256
      SOGA; Protein SOGA
      pfam14818
      Location:890 → 1014
      DUF4482; Domain of unknown function (DUF4482)

    2. XM_028837989.1 → XP_028693822.1  microtubule cross-linking factor 1 isoform X7

      UniProtKB/TrEMBL
      A0A1D5QQ00
      Related
      ENSMMUP00000047800.2, ENSMMUT00000075580.2
      Conserved Domains (3) summary
      TIGR02168
      Location:14 → 343
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:188 → 282
      SOGA; Protein SOGA
      pfam14818
      Location:957 → 1081
      DUF4482; Domain of unknown function (DUF4482)

    3. XM_028837983.1 → XP_028693816.1  microtubule cross-linking factor 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R2T2
      Conserved Domains (3) summary
      TIGR02168
      Location:14 → 343
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:188 → 282
      SOGA; Protein SOGA
      pfam14818
      Location:957 → 1081
      DUF4482; Domain of unknown function (DUF4482)

    4. XM_028837987.1 → XP_028693820.1  microtubule cross-linking factor 1 isoform X5

      UniProtKB/TrEMBL
      A0A1D5R2T2
      Conserved Domains (3) summary
      TIGR02168
      Location:14 → 343
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:188 → 282
      SOGA; Protein SOGA
      pfam14818
      Location:957 → 1053
      DUF4482; Domain of unknown function (DUF4482)

    5. XM_028837985.1 → XP_028693818.1  microtubule cross-linking factor 1 isoform X3

      UniProtKB/TrEMBL
      A0A1D5R2T2
      Related
      ENSMMUP00000074767.1, ENSMMUT00000095942.1
      Conserved Domains (3) summary
      TIGR02168
      Location:14 → 343
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:188 → 282
      SOGA; Protein SOGA
      pfam14818
      Location:947 → 1071
      DUF4482; Domain of unknown function (DUF4482)

    6. XM_028837988.1 → XP_028693821.1  microtubule cross-linking factor 1 isoform X6

      UniProtKB/TrEMBL
      A0A1D5R2T2
      Related
      ENSMMUP00000020694.4, ENSMMUT00000022121.4
      Conserved Domains (3) summary
      TIGR02168
      Location:14 → 343
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:188 → 282
      SOGA; Protein SOGA
      pfam14818
      Location:916 → 1040
      DUF4482; Domain of unknown function (DUF4482)

    7. XM_028837984.1 → XP_028693817.1  microtubule cross-linking factor 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5R2T2
      Conserved Domains (3) summary
      TIGR02168
      Location:1 → 342
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:187 → 281
      SOGA; Protein SOGA
      pfam14818
      Location:956 → 1080
      DUF4482; Domain of unknown function (DUF4482)

    8. XM_028837991.1 → XP_028693824.1  microtubule cross-linking factor 1 isoform X8

      UniProtKB/TrEMBL
      A0A1D5QQ00
      Conserved Domains (3) summary
      TIGR02168
      Location:1 → 317
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:162 → 256
      SOGA; Protein SOGA
      pfam14818
      Location:931 → 1055
      DUF4482; Domain of unknown function (DUF4482)

    9. XM_028837986.1 → XP_028693819.1  microtubule cross-linking factor 1 isoform X4

      UniProtKB/TrEMBL
      A0A1D5R2T2
      Related
      ENSMMUP00000072270.1, ENSMMUT00000085433.1
      Conserved Domains (4) summary
      COG1196
      Location:818 → 979
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:1 → 317
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:162 → 256
      SOGA; Protein SOGA
      pfam14818
      Location:931 → 1055
      DUF4482; Domain of unknown function (DUF4482)

    10. XM_028837992.1 → XP_028693825.1  microtubule cross-linking factor 1 isoform X10

      UniProtKB/TrEMBL
      A0A1D5QQ00
      Conserved Domains (4) summary
      COG1196
      Location:16 → 395
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:838 → 986
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:167 → 261
      SOGA; Protein SOGA
      pfam14818
      Location:936 → 1060
      DUF4482; Domain of unknown function (DUF4482)

    11. XM_028837993.1 → XP_028693826.1  microtubule cross-linking factor 1 isoform X11

      UniProtKB/TrEMBL
      G7NST4
      Conserved Domains (3) summary
      TIGR02168
      Location:709 → 857
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:38 → 132
      SOGA; Protein SOGA
      pfam14818
      Location:807 → 931
      DUF4482; Domain of unknown function (DUF4482)

    12. XM_028837994.1 → XP_028693827.1  microtubule cross-linking factor 1 isoform X12

      UniProtKB/TrEMBL
      G7NST4
      Conserved Domains (3) summary
      TIGR02168
      Location:708 → 856
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:37 → 131
      SOGA; Protein SOGA
      pfam14818
      Location:806 → 930
      DUF4482; Domain of unknown function (DUF4482)

    13. XM_028837995.1 → XP_028693828.1  microtubule cross-linking factor 1 isoform X13

      UniProtKB/TrEMBL
      G7NST4
      Conserved Domains (3) summary
      TIGR02168
      Location:683 → 831
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam11365
      Location:12 → 106
      SOGA; Protein SOGA
      pfam14818
      Location:781 → 905
      DUF4482; Domain of unknown function (DUF4482)
    Nucleotide Protein
    Heading Accession and Version

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