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    PARD6B par-6 family cell polarity regulator beta [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712004, updated on 17-Aug-2024

    Summary

    Official Symbol
    PARD6Bprovided by VGNC
    Official Full Name
    par-6 family cell polarity regulator betaprovided by VGNC
    Primary source
    VGNC:VGNC:107850
    See related
    Ensembl:ENSMMUG00000064108
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See PARD6B in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (85971414..85992712)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (13640682..13659890, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene RIPOR family member 3 Neighboring gene uncharacterized LOC114670505 Neighboring gene U6 spliceosomal RNA Neighboring gene breast carcinoma amplified sequence 4 Neighboring gene 26S proteasome non-ATPase regulatory subunit 10 pseudogene Neighboring gene activity dependent neuroprotector homeobox

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein kinase C binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in centrosome cycle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in establishment or maintenance of cell polarity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of cellular localization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    partitioning defective 6 homolog beta
    Names
    par-6 partitioning defective 6 homolog beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      85971414..85992712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148783.2XP_015004269.2  partitioning defective 6 homolog beta

      UniProtKB/TrEMBL
      G7N4J5, I0FVR0
      Related
      ENSMMUP00000068773.1, ENSMMUT00000092276.1
      Conserved Domains (2) summary
      cd06403
      Location:1796
      PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
      cd00992
      Location:156247
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...