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    PARP12 poly(ADP-ribose) polymerase family member 12 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711660, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PARP12provided by VGNC
    Official Full Name
    poly(ADP-ribose) polymerase family member 12provided by VGNC
    Primary source
    VGNC:VGNC:81734
    See related
    Ensembl:ENSMMUG00000004224
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PARP12 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (166442121..166482743, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (166409936..166450648, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene homeodomain interacting protein kinase 2 Neighboring gene uncharacterized LOC106997691 Neighboring gene thromboxane A synthase 1 Neighboring gene lysine demethylase 7A Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    poly [ADP-ribose] polymerase 12; protein mono-ADP-ribosyltransferase PARP12
    XP_014990530.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      166442121..166482743 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015135044.2 → XP_014990530.1  protein mono-ADP-ribosyltransferase PARP12

      UniProtKB/TrEMBL
      F6Z321, G7MMN7, H9ZCG0
      Related
      ENSMMUP00000005646.4, ENSMMUT00000005996.4
      Conserved Domains (5) summary
      smart00678
      Location:299 → 372
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      smart00356
      Location:177 → 200
      ZnF_C3H1; zinc finger
      cd01439
      Location:561 → 677
      TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
      pfam00644
      Location:497 → 677
      PARP; Poly(ADP-ribose) polymerase catalytic domain
      pfam02825
      Location:377 → 458
      WWE; WWE domain
    Nucleotide Protein
    Heading Accession and Version

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