U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TMPRSS3 transmembrane serine protease 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714500, updated on 17-Aug-2024

    Summary

    Official Symbol
    TMPRSS3provided by VGNC
    Official Full Name
    transmembrane serine protease 3provided by VGNC
    Primary source
    VGNC:VGNC:78576
    See related
    Ensembl:ENSMMUG00000018079
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TMPRSS3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (4274887..4298390)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (4289983..4314683)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene radial spoke head component 1 Neighboring gene ubiquitin associated and SH3 domain containing A Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114676798 Neighboring gene trefoil factor 1 Neighboring gene trefoil factor 2

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    transmembrane protease serine 3
    Names
    transmembrane protease, serine 3
    XP_014988312.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      4274887..4298390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015132826.2XP_014988312.2  transmembrane protease serine 3

      UniProtKB/TrEMBL
      F7EGM1, G7MMJ8
      Related
      ENSMMUP00000023760.4, ENSMMUT00000025397.4
      Conserved Domains (3) summary
      cd00112
      Location:158191
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd00190
      Location:301530
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam15494
      Location:196294
      SRCR_2; Scavenger receptor cysteine-rich domain