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    MAP3K12 mitogen-activated protein kinase kinase kinase 12 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703059, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAP3K12provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase kinase 12provided by VGNC
    Primary source
    VGNC:VGNC:74493
    Locus tag
    EGK_03714
    See related
    Ensembl:ENSMMUG00000006613
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAP3K12 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (53059220..53078061, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (52128427..52147370, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene proline rich 13 Neighboring gene poly(rC) binding protein 2 Neighboring gene TARBP2 subunit of RISC loading complex Neighboring gene neuropeptide FF-amide peptide precursor Neighboring gene activating transcription factor 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein autophosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 12
    NP_001247741.1
    XP_015007289.1
    XP_015007290.1
    XP_028684695.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260812.1 → NP_001247741.1  mitogen-activated protein kinase kinase kinase 12

      See identical proteins and their annotated locations for NP_001247741.1

      Status: PROVISIONAL

      Source sequence(s)
      JU336317
      UniProtKB/TrEMBL
      A0A8J8XVU7, F7HKE5, G7N751, H9FZL1
      Related
      ENSMMUP00000071549.1, ENSMMUT00000100996.1
      Conserved Domains (2) summary
      smart00219
      Location:165 → 397
      TyrKc; Tyrosine kinase, catalytic domain
      cd14059
      Location:164 → 400
      STKc_MAP3K12_13; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      53059220..53078061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151804.2 → XP_015007290.1  mitogen-activated protein kinase kinase kinase 12 isoform X2

      UniProtKB/TrEMBL
      F7HKE5, H9FZL0
      Conserved Domains (1) summary
      cd14059
      Location:131 → 367
      STKc_MAP3K12_13; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13

    2. XM_015151803.2 → XP_015007289.1  mitogen-activated protein kinase kinase kinase 12 isoform X1

      UniProtKB/TrEMBL
      A0A8J8XVU7, F7HKE5, G7N751, H9FZL1
      Conserved Domains (2) summary
      smart00219
      Location:165 → 397
      TyrKc; Tyrosine kinase, catalytic domain
      cd14059
      Location:164 → 400
      STKc_MAP3K12_13; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13

    3. XM_028828862.1 → XP_028684695.1  mitogen-activated protein kinase kinase kinase 12 isoform X2

      UniProtKB/TrEMBL
      F7HKE5, H9FZL0
      Related
      ENSMMUP00000008693.4, ENSMMUT00000009252.4
      Conserved Domains (1) summary
      cd14059
      Location:131 → 367
      STKc_MAP3K12_13; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13
    Nucleotide Protein
    Heading Accession and Version

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