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    NLRP4 NLR family pyrin domain containing 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703431, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NLRP4provided by VGNC
    Official Full Name
    NLR family pyrin domain containing 4provided by VGNC
    Primary source
    VGNC:VGNC:75233
    See related
    Ensembl:ENSMMUG00000028711
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human all
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    Genomic context

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    See NLRP4 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (55610735..55641024)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (53257579..53300398, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene ret finger protein-like 4A Neighboring gene NLR family pyrin domain containing 11 Neighboring gene NLR family pyrin domain containing 13 Neighboring gene NLR family pyrin domain containing 8 Neighboring gene NLR family pyrin domain containing 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NACHT, LRR and PYD domains-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      55610735..55641024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028839258.1 → XP_028695091.1  NACHT, LRR and PYD domains-containing protein 4

      UniProtKB/TrEMBL
      F7H800, G7NNW1
      Related
      ENSMMUP00000031420.2, ENSMMUT00000038321.3
      Conserved Domains (4) summary
      cd08320
      Location:11 → 92
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00034
      Location:725 → 752
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:149 → 318
      NACHT; NACHT domain
      cl29113
      Location:685 → 957
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein
    Heading Accession and Version

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