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    HES2 hes family bHLH transcription factor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703404, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HES2provided by VGNC
    Official Full Name
    hes family bHLH transcription factor 2provided by VGNC
    Primary source
    VGNC:VGNC:73174
    See related
    Ensembl:ENSMMUG00000022882
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HES2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (218101443..218106135)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (5554258..5558975, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene TNF receptor superfamily member 25 Neighboring gene espin Neighboring gene acyl-CoA thioesterase 7 Neighboring gene G protein-coupled receptor 153

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anterior/posterior pattern specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor HES-2
    Names
    hairy and enhancer of split 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      218101443..218106135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001092640.4 → XP_001092640.1  transcription factor HES-2

      See identical proteins and their annotated locations for XP_001092640.1

      UniProtKB/TrEMBL
      A0A1D5R8B9
      Related
      ENSMMUP00000056559.1, ENSMMUT00000078976.2
      Conserved Domains (2) summary
      smart00511
      Location:84 → 127
      ORANGE; Orange domain
      cd00083
      Location:12 → 70
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    Nucleotide Protein
    Heading Accession and Version

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