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    MAPKAPK5 MAPK activated protein kinase 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713521, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MAPKAPK5provided by VGNC
    Official Full Name
    MAPK activated protein kinase 5provided by VGNC
    Primary source
    VGNC:VGNC:74655
    Locus tag
    EGK_04198
    See related
    Ensembl:ENSMMUG00000022353
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAPKAPK5 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (111513795..111565418)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (111935803..111964712, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 2 family member Neighboring gene endogenous retrovirus group K member 6 Env polyprotein-like Neighboring gene endogenous retrovirus group K member 25 Env polyprotein-like Neighboring gene putative uncharacterized protein encoded by MAPKAPK5-AS1 Neighboring gene uncharacterized LOC106996134 Neighboring gene a disintegrin and metalloproteinase domain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium/calmodulin-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mitogen-activated protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of TOR signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein autophosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MAP kinase-activated protein kinase 5
    Names
    mitogen-activated protein kinase-activated protein kinase 5
    NP_001244779.1
    XP_028684812.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257850.1 → NP_001244779.1  MAP kinase-activated protein kinase 5

      See identical proteins and their annotated locations for NP_001244779.1

      Status: PROVISIONAL

      Source sequence(s)
      JU336852
      UniProtKB/TrEMBL
      A0A8J8XYT5, F6ZBS3, G7N5I2, H9G146
      Related
      ENSMMUP00000029425.4, ENSMMUT00000031447.4
      Conserved Domains (1) summary
      cd14171
      Location:15 → 304
      STKc_MAPKAPK5; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 5

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      111513795..111565418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828979.1 → XP_028684812.1  MAP kinase-activated protein kinase 5 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q845, F6ZBS3, H9ZEN3
      Related
      ENSMMUP00000044212.2, ENSMMUT00000075703.2
      Conserved Domains (1) summary
      cd14171
      Location:15 → 304
      STKc_MAPKAPK5; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 5
    Nucleotide Protein
    Heading Accession and Version

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