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    EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701193, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EHHADHprovided by VGNC
    Official Full Name
    enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenaseprovided by VGNC
    Primary source
    VGNC:VGNC:72179
    See related
    Ensembl:ENSMMUG00000053997
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EHHADH in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (90511021..90581694, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (107772508..107844635)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene chromosome 2 C3orf70 homolog Neighboring gene small nucleolar RNA SNORD43 Neighboring gene mitogen-activated protein kinase kinase kinase 13 Neighboring gene transmembrane protein 41A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3-hydroxyacyl-CoA dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NAD+ binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxisomal bifunctional enzyme
    Names
    enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase
    NP_001244421.1
    XP_014986901.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257492.1 → NP_001244421.1  peroxisomal bifunctional enzyme

      See identical proteins and their annotated locations for NP_001244421.1

      Status: PROVISIONAL

      Source sequence(s)
      JU323220
      UniProtKB/TrEMBL
      F7GFA8, G7MJ42
      Related
      ENSMMUP00000078129.1, ENSMMUT00000098290.1
      Conserved Domains (4) summary
      cd06558
      Location:8 → 188
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
      PRK11154
      Location:20 → 705
      fadJ; multifunctional fatty acid oxidation complex subunit alpha; Reviewed
      pfam00725
      Location:478 → 582
      3HCDH; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
      pfam02737
      Location:299 → 476
      3HCDH_N; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      90511021..90581694 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015131415.2 → XP_014986901.2  peroxisomal bifunctional enzyme isoform X1

      UniProtKB/TrEMBL
      A0A5F8AJN1
      Conserved Domains (1) summary
      PRK11154
      Location:2 → 609
      fadJ; multifunctional fatty acid oxidation complex subunit alpha; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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