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    EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719502, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EPS15L1provided by VGNC
    Official Full Name
    epidermal growth factor receptor pathway substrate 15 like 1provided by VGNC
    Primary source
    VGNC:VGNC:72100
    See related
    Ensembl:ENSMMUG00000000994
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EPS15L1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (15858659..15979622, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (16307135..16420941, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114674043 Neighboring gene KLF transcription factor 2 Neighboring gene calreticulin 3 Neighboring gene chromosome 19 C19orf44 homolog Neighboring gene calcium homeostasis endoplasmic reticulum protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosomal transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of clathrin coat of coated pit IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    epidermal growth factor receptor substrate 15-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      15858659..15979622 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028839734.1 → XP_028695567.1  epidermal growth factor receptor substrate 15-like 1 isoform X10

      UniProtKB/TrEMBL
      G7NMP3
      Conserved Domains (3) summary
      smart00027
      Location:121 → 214
      EH; Eps15 homology domain
      COG1196
      Location:385 → 569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00052
      Location:19 → 85
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...

    2. XM_028839732.1 → XP_028695565.1  epidermal growth factor receptor substrate 15-like 1 isoform X6

      UniProtKB/TrEMBL
      A0A5F8ARC3, G7NMP3
      Related
      ENSMMUP00000079455.1, ENSMMUT00000080498.1
      Conserved Domains (3) summary
      smart00027
      Location:121 → 214
      EH; Eps15 homology domain
      COG1196
      Location:384 → 569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00052
      Location:19 → 85
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...

    3. XM_028839733.1 → XP_028695566.1  epidermal growth factor receptor substrate 15-like 1 isoform X7

      UniProtKB/TrEMBL
      A0A1D5R7A3, A0A5K1U0N1
      Related
      ENSMMUP00000056192.2, ENSMMUT00000058664.2
      Conserved Domains (3) summary
      smart00027
      Location:121 → 214
      EH; Eps15 homology domain
      COG1196
      Location:384 → 569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00052
      Location:19 → 85
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...

    4. XM_028839729.1 → XP_028695562.1  epidermal growth factor receptor substrate 15-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AS86, G7NMP3
      Related
      ENSMMUP00000079932.1, ENSMMUT00000080471.1
      Conserved Domains (3) summary
      smart00027
      Location:121 → 214
      EH; Eps15 homology domain
      COG1196
      Location:384 → 569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00052
      Location:19 → 85
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...

    5. XM_028839728.1 → XP_028695561.1  epidermal growth factor receptor substrate 15-like 1 isoform X1

      UniProtKB/TrEMBL
      F6SR49, G7NMP3, H9ENG8
      Related
      ENSMMUP00000001338.4, ENSMMUT00000001421.4
      Conserved Domains (3) summary
      smart00027
      Location:121 → 214
      EH; Eps15 homology domain
      COG1196
      Location:384 → 569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00052
      Location:19 → 85
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...

    6. XM_028839730.1 → XP_028695563.1  epidermal growth factor receptor substrate 15-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F8ACX6
      Related
      ENSMMUP00000075725.1, ENSMMUT00000097268.1
      Conserved Domains (3) summary
      smart00027
      Location:105 → 193
      EH; Eps15 homology domain
      COG1196
      Location:363 → 548
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00052
      Location:19 → 85
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...

    7. XM_028839731.1 → XP_028695564.1  epidermal growth factor receptor substrate 15-like 1 isoform X5

      UniProtKB/TrEMBL
      G7NMP3
      Conserved Domains (2) summary
      smart00027
      Location:24 → 117
      EH; Eps15 homology domain
      COG1196
      Location:287 → 472
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    8. XM_015123218.2 → XP_014978704.1  epidermal growth factor receptor substrate 15-like 1 isoform X9

      UniProtKB/TrEMBL
      A0A1D5QFR2, A0A5K1U0N1
      Related
      ENSMMUP00000046882.1, ENSMMUT00000055421.2
      Conserved Domains (4) summary
      smart00027
      Location:121 → 214
      EH; Eps15 homology domain
      cd00052
      Location:131 → 196
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      pfam15619
      Location:385 → 555
      Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
      cl02488
      Location:385 → 572
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    9. XM_015123217.2 → XP_014978703.1  epidermal growth factor receptor substrate 15-like 1 isoform X8

      UniProtKB/TrEMBL
      A0A1D5QDB0
      Related
      ENSMMUP00000046029.2, ENSMMUT00000070482.2
      Conserved Domains (4) summary
      smart00027
      Location:24 → 117
      EH; Eps15 homology domain
      cd00052
      Location:34 → 99
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
      cd00176
      Location:288 → 475
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam15619
      Location:288 → 458
      Lebercilin; Ciliary protein causing Leber congenital amaurosis disease

    10. XM_015123214.2 → XP_014978700.2  epidermal growth factor receptor substrate 15-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZFC0, A0A5K1U0N1
      Related
      ENSMMUP00000063329.1, ENSMMUT00000081343.1
      Conserved Domains (3) summary
      smart00027
      Location:121 → 214
      EH; Eps15 homology domain
      COG1196
      Location:384 → 569
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00052
      Location:19 → 85
      EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...

    RNA

    1. XR_003725111.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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