CYP1B1 cytochrome P450 family 1 subfamily B member 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: CYP1B1provided by VGNC
Official Full Name: cytochrome P450 family 1 subfamily B member 1provided by VGNC
Primary source: VGNC:VGNC:103594
See related: Ensembl:ENSMMUG00000013945
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 13

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	13	NC_041766.1 (70840153..70848698)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	13	NC_027905.1 (38527819..38536368, complement)

Chromosome 13 - NC_041766.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

study identifed CYP1B1 genetic variants in 13 cynomolgus and 4 rhesus macaques; a total of 17 genetic variants were identified, including 8 non-synonymous genetic variants, indicating that, similar to humans, CYP1B1 is polymorphic in macaques
Title: CYP1B1 is polymorphic in cynomolgus and rhesus macaques.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

RH70529 (e-PCR)
- UniSTS:39763

Cyp1b1 (e-PCR), detects polymorphism
- UniSTS:468828

SHGC-12924 (e-PCR)
- UniSTS:83093

CYP1B1_568 (e-PCR)
- UniSTS:277150

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: cytochrome P450 1B1; cytochrome P450 family 1 subfamily B member 1

Names: cytochrome P450, family 1, subfamily B, polypeptide 1

NP_001253797.1

EC 1.14.14.1

XP_014967577.2

EC 1.14.14.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001266868.1 → NP_001253797.1 cytochrome P450 family 1 subfamily B member 1

See identical proteins and their annotated locations for NP_001253797.1

Status: PROVISIONAL

Source sequence(s)

JU474459

UniProtKB/TrEMBL

G7N9V0, H9Z5P7

Related

ENSMMUP00000018330.4, ENSMMUT00000019573.4

Conserved Domains (1) summary

pfam00067
Location:51 → 519

p450; Cytochrome P450

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041766.1 Reference Mmul_10 Primary Assembly

Range

70840153..70848698

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015112091.2 → XP_014967577.2 cytochrome P450 1B1 isoform X1

UniProtKB/TrEMBL

F6SEA8

Conserved Domains (1) summary

pfam00067
Location:56 → 524

p450; Cytochrome P450