U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CD40 CD40 molecule [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707749, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CD40provided by VGNC
    Official Full Name
    CD40 moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:70703
    See related
    Ensembl:ENSMMUG00000003683
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CD40 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (81311826..81322796)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (18364421..18377277, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor coactivator 5 Neighboring gene 60S ribosomal protein L13 pseudogene Neighboring gene cadherin 22 Neighboring gene solute carrier family 35 member C2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables antigen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in B cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in CD40 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in TRIF-dependent toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to interleukin-1 IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to tumor necrosis factor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to protozoan IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response-regulating cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of B cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of blood vessel endothelial cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of endothelial cell apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of interleukin-12 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of isotype switching to IgG isotypes IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to type II interferon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CD40 receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tumor necrosis factor receptor superfamily member 5

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265862.1 → NP_001252791.1  tumor necrosis factor receptor superfamily member 5 precursor

      See identical proteins and their annotated locations for NP_001252791.1

      Status: PROVISIONAL

      Source sequence(s)
      JU477940
      UniProtKB/TrEMBL
      F6SNI1, G7N4M5, H9ZFM8
      Related
      ENSMMUP00000004910.3, ENSMMUT00000005213.4
      Conserved Domains (1) summary
      cd13407
      Location:26 → 186
      TNFRSF5; Tumor necrosis factor receptor superfamily member 5 (TNFRSF5), also known as CD40

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      81311826..81322796
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148819.2 → XP_015004305.1  tumor necrosis factor receptor superfamily member 5 isoform X1

      UniProtKB/TrEMBL
      G7N4M5
      Conserved Domains (1) summary
      cd13407
      Location:26 → 186
      TNFRSF5; Tumor necrosis factor receptor superfamily member 5 (TNFRSF5), also known as CD40

    2. XM_028827313.1 → XP_028683146.1  tumor necrosis factor receptor superfamily member 5 isoform X2

      Conserved Domains (2) summary
      cd00185
      Location:62 → 103
      TNFRSF; CRD2 [structural motif]
      cl22855
      Location:26 → 135
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    3. XM_028827315.1 → XP_028683148.1  tumor necrosis factor receptor superfamily member 5 isoform X4

      Conserved Domains (1) summary
      cd13407
      Location:26 → 186
      TNFRSF5; Tumor necrosis factor receptor superfamily member 5 (TNFRSF5), also known as CD40

    4. XM_028827314.1 → XP_028683147.1  tumor necrosis factor receptor superfamily member 5 isoform X3

      UniProtKB/TrEMBL
      G7N4M5
      Conserved Domains (1) summary
      cd13407
      Location:26 → 186
      TNFRSF5; Tumor necrosis factor receptor superfamily member 5 (TNFRSF5), also known as CD40
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.