PDLIM5 PDZ and LIM domain 5 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PDLIM5provided by VGNC
Official Full Name: PDZ and LIM domain 5provided by VGNC
Primary source: VGNC:VGNC:75816
See related: Ensembl:ENSMMUG00000022246
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	5	NC_041758.1 (92828458..93039669)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	5	NC_027897.1 (92971699..93182925)

Chromosome 5 - NC_041758.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

L17705 (e-PCR)
- UniSTS:66091

D8S2279 (e-PCR)
- UniSTS:473907

RH91857 (e-PCR)
- UniSTS:88158

D4S964 (e-PCR)
- UniSTS:66400

RH36106 (e-PCR)
- UniSTS:1382

D4S2569E (e-PCR)
- UniSTS:19561

D10S16 (e-PCR)
- UniSTS:155756

SHGC-63475 (e-PCR)
- UniSTS:5487

SHGC-59267 (e-PCR)
- UniSTS:57977

SHGC-67609 (e-PCR)
- UniSTS:54969

D4S1159 (e-PCR)
- UniSTS:59834

STS-AA009657 (e-PCR)
- UniSTS:69085

SHGC-63474 (e-PCR)
- UniSTS:15587

RH91416 (e-PCR)
- UniSTS:88822

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables muscle alpha-actinin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heart development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in muscle structure development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in Z disc	IEA Inferred from Electronic Annotation more info	PubMed
located_in adherens junction	IEA Inferred from Electronic Annotation more info	PubMed
part_of filamentous actin	IEA Inferred from Electronic Annotation more info	PubMed
located_in stress fiber	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: PDZ and LIM domain protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041758.1 Reference Mmul_10 Primary Assembly

Range

92828458..93039669

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015138810.2 → XP_014994296.1 PDZ and LIM domain protein 5 isoform X1

UniProtKB/TrEMBL

F6YVJ0

Conserved Domains (5) summary

cd09453
Location:563 → 614

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:622 → 673

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:681 → 735

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:214 → 305

DUF4749; Domain of unknown function (DUF4749)
XM_015138818.2 → XP_014994304.1 PDZ and LIM domain protein 5 isoform X8

UniProtKB/TrEMBL

A0A5F8A0C7, G7MTE9

Related

ENSMMUP00000071365.1, ENSMMUT00000084119.1

Conserved Domains (5) summary

cd09453
Location:431 → 482

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:490 → 541

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:549 → 603

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:214 → 305

DUF4749; Domain of unknown function (DUF4749)
XM_015138813.2 → XP_014994299.1 PDZ and LIM domain protein 5 isoform X2

UniProtKB/TrEMBL

F6YVJ0

Related

ENSMMUP00000029290.4, ENSMMUT00000031299.4

Conserved Domains (5) summary

cd09453
Location:558 → 609

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:617 → 668

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:676 → 730

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:214 → 300

DUF4749; Domain of unknown function (DUF4749)
XM_028848630.1 → XP_028704463.1 PDZ and LIM domain protein 5 isoform X10

UniProtKB/TrEMBL

A0A5F8AJP2, G7MTE9

Related

ENSMMUP00000077159.1, ENSMMUT00000090410.1

Conserved Domains (6) summary

cd09453
Location:426 → 477

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:485 → 536

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:544 → 598

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

PHA03307
Location:82 → 445

PHA03307; transcriptional regulator ICP4; Provisional

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:214 → 300

DUF4749; Domain of unknown function (DUF4749)
XM_015138814.2 → XP_014994300.1 PDZ and LIM domain protein 5 isoform X3

UniProtKB/TrEMBL

F6YVJ0

Conserved Domains (5) summary

cd09453
Location:552 → 603

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:611 → 662

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:670 → 724

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:214 → 294

DUF4749; Domain of unknown function (DUF4749)
XM_001103447.3 → XP_001103447.1 PDZ and LIM domain protein 5 isoform X11

UniProtKB/TrEMBL

A0A5F7ZFI6, G7MTE9

Related

ENSMMUP00000064360.1, ENSMMUT00000082689.1

Conserved Domains (6) summary

cd09453
Location:420 → 471

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:479 → 530

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:538 → 592

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15741
Location:82 → 402

LRIF1; Ligand-dependent nuclear receptor-interacting factor 1

pfam15936
Location:214 → 294

DUF4749; Domain of unknown function (DUF4749)
XM_015138815.2 → XP_014994301.1 PDZ and LIM domain protein 5 isoform X4

UniProtKB/TrEMBL

A0A5F8ADV7

Conserved Domains (5) summary

cd09453
Location:454 → 505

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:513 → 564

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:572 → 626

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:105 → 196

DUF4749; Domain of unknown function (DUF4749)
XM_015138816.2 → XP_014994302.1 PDZ and LIM domain protein 5 isoform X5

UniProtKB/TrEMBL

A0A5F8ADV7, F6Z107

Related

ENSMMUP00000029288.3, ENSMMUT00000031297.3

Conserved Domains (5) summary

cd09453
Location:449 → 500

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:508 → 559

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:567 → 621

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:105 → 191

DUF4749; Domain of unknown function (DUF4749)
XM_015138820.2 → XP_014994306.1 PDZ and LIM domain protein 5 isoform X12

UniProtKB/TrEMBL

A0A5F8ADV7

Conserved Domains (6) summary

PHA03381
Location:132 → 334

PHA03381; tegument protein VP22; Provisional

cd09453
Location:317 → 368

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:435 → 489

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:105 → 191

DUF4749; Domain of unknown function (DUF4749)

cl02475
Location:376 → 427

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
XM_015138817.2 → XP_014994303.1 PDZ and LIM domain protein 5 isoform X6

UniProtKB/TrEMBL

A0A5F8ADV7

Conserved Domains (5) summary

cd09453
Location:443 → 494

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:502 → 553

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:561 → 615

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:105 → 185

DUF4749; Domain of unknown function (DUF4749)
XM_015138822.2 → XP_014994308.1 PDZ and LIM domain protein 5 isoform X13

UniProtKB/TrEMBL

A0A5F8ADV7

Related

ENSMMUP00000075124.1, ENSMMUT00000080566.1

Conserved Domains (6) summary

PHA03381
Location:136 → 328

PHA03381; tegument protein VP22; Provisional

cd09453
Location:311 → 362

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:429 → 483

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:105 → 185

DUF4749; Domain of unknown function (DUF4749)

cl02475
Location:370 → 421

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
XM_015138819.2 → XP_014994305.1 PDZ and LIM domain protein 5 isoform X9

UniProtKB/TrEMBL

A0A5F8ADV7

Conserved Domains (5) summary

cd09453
Location:429 → 480

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:488 → 539

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:547 → 601

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:100 → 171

DUF4749; Domain of unknown function (DUF4749)
XM_015138823.2 → XP_014994309.2 PDZ and LIM domain protein 5 isoform X15

UniProtKB/TrEMBL

F6Z153

Related

ENSMMUP00000029283.4, ENSMMUT00000031292.4

Conserved Domains (2) summary

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:105 → 191

DUF4749; Domain of unknown function (DUF4749)
XM_015138824.2 → XP_014994310.2 PDZ and LIM domain protein 5 isoform X16

UniProtKB/TrEMBL

F6Z147, F6Z153

Related

ENSMMUP00000029285.4, ENSMMUT00000031294.4

Conserved Domains (2) summary

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:91 → 171

DUF4749; Domain of unknown function (DUF4749)
XM_015138811.2 → XP_014994297.1 PDZ and LIM domain protein 5 isoform X1

UniProtKB/TrEMBL

F6YVJ0

Conserved Domains (5) summary

cd09453
Location:563 → 614

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:622 → 673

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:681 → 735

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:214 → 305

DUF4749; Domain of unknown function (DUF4749)
XM_015138812.2 → XP_014994298.1 PDZ and LIM domain protein 5 isoform X1

UniProtKB/TrEMBL

F6YVJ0

Conserved Domains (5) summary

cd09453
Location:563 → 614

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:622 → 673

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:681 → 735

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

cd00992
Location:10 → 82

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam15936
Location:214 → 305

DUF4749; Domain of unknown function (DUF4749)
XM_028848629.1 → XP_028704462.1 PDZ and LIM domain protein 5 isoform X7

UniProtKB/TrEMBL

F6YVJ0

Conserved Domains (4) summary

cd09453
Location:436 → 487

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cd09457
Location:495 → 546

LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family

cd09459
Location:554 → 608

LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family

pfam15936
Location:92 → 178

DUF4749; Domain of unknown function (DUF4749)
XM_028848631.1 → XP_028704464.1 PDZ and LIM domain protein 5 isoform X14

Conserved Domains (2) summary

cd09453
Location:95 → 146

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cl02475
Location:213 → 267

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
XM_028848632.1 → XP_028704465.1 PDZ and LIM domain protein 5 isoform X14

Conserved Domains (2) summary

cd09453
Location:95 → 146

LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family

cl02475
Location:213 → 267

LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers