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    CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709315, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CELSR3provided by VGNC
    Official Full Name
    cadherin EGF LAG seven-pass G-type receptor 3provided by VGNC
    Primary source
    VGNC:VGNC:71148
    See related
    Ensembl:ENSMMUG00000014707
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CELSR3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (104697679..104723773, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (93784604..93812403)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106996924 Neighboring gene transmembrane protein 89 Neighboring gene solute carrier family 26 member 6 Neighboring gene uncharacterized LOC114676346 Neighboring gene NCK interacting protein with SH3 domain

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cadherin EGF LAG seven-pass G-type receptor 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      104697679..104723773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015130983.2 → XP_014986469.2  cadherin EGF LAG seven-pass G-type receptor 3 isoform X3

      UniProtKB/TrEMBL
      F7GBV2, G7MIP5
      Related
      ENSMMUP00000019312.4, ENSMMUT00000020638.4
      Conserved Domains (11) summary
      smart00303
      Location:2476 → 2529
      GPS; G-protein-coupled receptor proteolytic site domain
      cd11304
      Location:655 → 752
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00008
      Location:2126 → 2185
      HormR; Domain present in hormone receptors
      cd00054
      Location:1982 → 2020
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:2076 → 2114
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1517 → 1700
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03363
      Location:66 → 184
      Herpes_LP; Herpesvirus leader protein
      pfam00053
      Location:2003 → 2042
      Laminin_EGF; Laminin EGF domain
      pfam16489
      Location:2204 → 2450
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:2539 → 2563
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:2536 → 2788
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_015130980.2 → XP_014986466.2  cadherin EGF LAG seven-pass G-type receptor 3 isoform X4

      UniProtKB/TrEMBL
      G7MIP5
      Conserved Domains (11) summary
      smart00303
      Location:2481 → 2534
      GPS; G-protein-coupled receptor proteolytic site domain
      cd11304
      Location:655 → 752
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00008
      Location:2126 → 2190
      HormR; Domain present in hormone receptors
      cd00054
      Location:1982 → 2020
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:2076 → 2114
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1517 → 1700
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03363
      Location:66 → 184
      Herpes_LP; Herpesvirus leader protein
      pfam00053
      Location:2003 → 2042
      Laminin_EGF; Laminin EGF domain
      pfam16489
      Location:2209 → 2455
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:2544 → 2568
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:2541 → 2794
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_015130982.2 → XP_014986468.2  cadherin EGF LAG seven-pass G-type receptor 3 isoform X2

      UniProtKB/TrEMBL
      G7MIP5
      Conserved Domains (11) summary
      smart00303
      Location:2476 → 2529
      GPS; G-protein-coupled receptor proteolytic site domain
      cd11304
      Location:655 → 752
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00008
      Location:2126 → 2185
      HormR; Domain present in hormone receptors
      cd00054
      Location:1982 → 2020
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:2076 → 2114
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1517 → 1700
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03363
      Location:66 → 184
      Herpes_LP; Herpesvirus leader protein
      pfam00053
      Location:2003 → 2042
      Laminin_EGF; Laminin EGF domain
      pfam16489
      Location:2204 → 2450
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:2539 → 2563
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:2536 → 2789
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    4. XM_015130981.2 → XP_014986467.2  cadherin EGF LAG seven-pass G-type receptor 3 isoform X1

      UniProtKB/TrEMBL
      G7MIP5
      Conserved Domains (11) summary
      smart00303
      Location:2481 → 2534
      GPS; G-protein-coupled receptor proteolytic site domain
      cd11304
      Location:655 → 752
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00008
      Location:2126 → 2190
      HormR; Domain present in hormone receptors
      cd00054
      Location:1982 → 2020
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00055
      Location:2076 → 2114
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1517 → 1700
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam03363
      Location:66 → 184
      Herpes_LP; Herpesvirus leader protein
      pfam00053
      Location:2003 → 2042
      Laminin_EGF; Laminin EGF domain
      pfam16489
      Location:2209 → 2455
      GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
      cd14964
      Location:2544 → 2568
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:2541 → 2793
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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