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    GSTP1 glutathione S-transferase pi 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 721704, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GSTP1provided by VGNC
    Official Full Name
    glutathione S-transferase pi 1provided by VGNC
    Primary source
    VGNC:VGNC:101091
    See related
    Ensembl:ENSMMUG00000018524
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human all
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    Genomic context

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    See GSTP1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (6930750..6933187, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (6788948..6791401, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene double C2 domain gamma Neighboring gene NADH:ubiquinone oxidoreductase core subunit V1 Neighboring gene uncharacterized protein C11orf72-like Neighboring gene uncharacterized LOC114672223 Neighboring gene calcium binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The mRNA for GST Pi from FRHK rhesus monkey kidney cells codes for an enzyme with activity towards 1-chloro-2,4-dinitrobenzene in spite of an I68F mutation. Swedmark S, et al. Gene, 1998 Jan 5. PMID 9461421
    2. Systematic identification and characterization of glutathione S-transferases in cynomolgus macaque. Uno Y, et al. Biochem Pharmacol, 2013 Sep 1. PMID 23827461
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutathione transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutathione S-transferase P
    Names
    GST class-pi
    GST-pi enzyme
    glutathione S-transferase P1
    NP_001036141.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042676.1 → NP_001036141.1  glutathione S-transferase P

      See identical proteins and their annotated locations for NP_001036141.1

      Status: PROVISIONAL

      Source sequence(s)
      L49501
      UniProtKB/Swiss-Prot
      Q28514
      UniProtKB/TrEMBL
      F7A2W2, G7NBW9, H9Z845
      Related
      ENSMMUP00000024369.3, ENSMMUT00000026042.4
      Conserved Domains (2) summary
      cd03210
      Location:84 → 210
      GST_C_Pi; C-terminal, alpha helical domain of Class Pi Glutathione S-transferases
      cd03076
      Location:3 → 76
      GST_N_Pi; GST_N family, Class Pi subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      6930750..6933187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28514.3 GenPept UniProtKB/Swiss-Prot:Q28514

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