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    MMP25 matrix metallopeptidase 25 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700486, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MMP25provided by VGNC
    Official Full Name
    matrix metallopeptidase 25provided by VGNC
    Primary source
    VGNC:VGNC:74747
    See related
    Ensembl:ENSMMUG00000009483
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MMP25 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (3117177..3131967)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (3860597..3875400, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene THO complex subunit 6 Neighboring gene BICD family like cargo adaptor 2 Neighboring gene putative uncharacterized protein FLJ46214 Neighboring gene sialidase-like Neighboring gene U1 spliceosomal RNA Neighboring gene zinc finger and SCAN domain-containing protein 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in collagen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    matrix metalloproteinase-25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      3117177..3131967
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001091146.4 → XP_001091146.2  matrix metalloproteinase-25 isoform X2

      UniProtKB/TrEMBL
      A0A5F8A932, F6YUR1
      Related
      ENSMMUP00000012407.3, ENSMMUT00000013237.4
      Conserved Domains (4) summary
      cd00094
      Location:315 → 508
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cd04278
      Location:115 → 280
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
      pfam00413
      Location:115 → 280
      Peptidase_M10; Matrixin
      pfam01471
      Location:25 → 85
      PG_binding_1; Putative peptidoglycan binding domain

    2. XM_028841453.1 → XP_028697286.1  matrix metalloproteinase-25 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A932
      Conserved Domains (2) summary
      cd00094
      Location:259 → 418
      HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
      cd04278
      Location:59 → 224
      ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    Nucleotide Protein
    Heading Accession and Version

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