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    PPP1R12A protein phosphatase 1 regulatory subunit 12A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695735, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PPP1R12Aprovided by VGNC
    Official Full Name
    protein phosphatase 1 regulatory subunit 12Aprovided by VGNC
    Primary source
    VGNC:VGNC:76362
    See related
    Ensembl:ENSMMUG00000019214
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PPP1R12A in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (79334006..79496788, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (78649376..78812308, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene nucleolar protein 56-like Neighboring gene pro-apoptotic WT1 regulator Neighboring gene uncharacterized LOC107000948 Neighboring gene small nuclear ribonucleoprotein G pseudogene Neighboring gene 60S ribosomal protein L7-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables enzyme inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in A band IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase 1 regulatory subunit 12A
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 12A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266093.1 → NP_001253022.1  protein phosphatase 1 regulatory subunit 12A

      See identical proteins and their annotated locations for NP_001253022.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047135
      UniProtKB/TrEMBL
      F6QPG9, H9Z978, I0FRY0
      Related
      ENSMMUP00000025253.4, ENSMMUT00000026993.4
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:930 → 1028
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      79334006..79496788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152305.2 → XP_015007791.1  protein phosphatase 1 regulatory subunit 12A isoform X12

      UniProtKB/TrEMBL
      F6QPK6
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:815 → 913
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    2. XM_015152298.2 → XP_015007784.1  protein phosphatase 1 regulatory subunit 12A isoform X5

      UniProtKB/TrEMBL
      H9Z978
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:918 → 1016
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    3. XM_015152304.2 → XP_015007790.1  protein phosphatase 1 regulatory subunit 12A isoform X11

      UniProtKB/TrEMBL
      H9Z978
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:854 → 952
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    4. XM_015152299.2 → XP_015007785.1  protein phosphatase 1 regulatory subunit 12A isoform X6

      UniProtKB/TrEMBL
      F6QPK6
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:913 → 1011
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    5. XM_015152296.2 → XP_015007782.1  protein phosphatase 1 regulatory subunit 12A isoform X2

      UniProtKB/TrEMBL
      H9Z978
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:957 → 1055
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    6. XM_015152300.2 → XP_015007786.1  protein phosphatase 1 regulatory subunit 12A isoform X7

      UniProtKB/TrEMBL
      H9Z978
      Related
      ENSMMUP00000070186.1, ENSMMUT00000106836.1
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:910 → 1008
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    7. XM_015152295.2 → XP_015007781.1  protein phosphatase 1 regulatory subunit 12A isoform X1

      UniProtKB/TrEMBL
      H9Z978
      Related
      ENSMMUP00000049830.2, ENSMMUT00000070237.2
      Conserved Domains (5) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:47 → 136
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:199 → 252
      Ank_4; Ankyrin repeats (many copies)
      pfam15898
      Location:969 → 1067
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]

    8. XM_028828811.1 → XP_028684644.1  protein phosphatase 1 regulatory subunit 12A isoform X4

      UniProtKB/TrEMBL
      H9Z978
      Conserved Domains (4) summary
      PHA03095
      Location:43 → 272
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:47 → 136
      Ank_2; Ankyrin repeats (3 copies)
      pfam15898
      Location:969 → 1023
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    9. XM_015152297.2 → XP_015007783.1  protein phosphatase 1 regulatory subunit 12A isoform X3

      UniProtKB/TrEMBL
      H9Z978
      Conserved Domains (5) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:47 → 136
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:199 → 252
      Ank_4; Ankyrin repeats (many copies)
      pfam15898
      Location:969 → 1023
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]

    10. XM_015152303.2 → XP_015007789.1  protein phosphatase 1 regulatory subunit 12A isoform X10

      UniProtKB/TrEMBL
      H9Z978
      Related
      ENSMMUP00000025257.4, ENSMMUT00000026998.4
      Conserved Domains (3) summary
      cd00204
      Location:67 → 252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:871 → 969
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    11. XM_028828812.1 → XP_028684645.1  protein phosphatase 1 regulatory subunit 12A isoform X8

      UniProtKB/TrEMBL
      H9Z978
      Conserved Domains (3) summary
      sd00045
      Location:115 → 146
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:120 → 189
      Ank_2; Ankyrin repeats (3 copies)
      pfam15898
      Location:886 → 984
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    12. XM_015152302.2 → XP_015007788.1  protein phosphatase 1 regulatory subunit 12A isoform X9

      UniProtKB/TrEMBL
      F6QPK6
      Related
      ENSMMUP00000025250.4, ENSMMUT00000026990.4
      Conserved Domains (3) summary
      PHA03095
      Location:43 → 272
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:72 → 103
      ANK; ANK repeat [structural motif]
      pfam15898
      Location:874 → 972
      PRKG1_interact; cGMP-dependent protein kinase interacting domain
    Nucleotide Protein
    Heading Accession and Version

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