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    IRAK2 interleukin 1 receptor associated kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698091, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IRAK2provided by VGNC
    Official Full Name
    interleukin 1 receptor associated kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:73758
    See related
    Ensembl:ENSMMUG00000019932
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IRAK2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (141563417..141643033)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (56081893..56162402, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene von Hippel-Lindau tumor suppressor Neighboring gene U6 spliceosomal RNA Neighboring gene TatD DNase domain containing 2 Neighboring gene nuclear transcription factor Y subunit beta pseudogene Neighboring gene uncharacterized LOC114676392

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interleukin-1-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interleukin-1 receptor-associated kinase-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      141563417..141643033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001090790.4 → XP_001090790.2  interleukin-1 receptor-associated kinase-like 2 isoform X1

      UniProtKB/TrEMBL
      A0A5S6R914, A0A8J8YJ78, F7GMD7, G7MKR0, H9F3E8
      Related
      ENSMMUP00000026192.3, ENSMMUT00000027998.4
      Conserved Domains (2) summary
      cd08795
      Location:3 → 91
      Death_IRAK2; Death domain of Interleukin 1 Receptor Associated Kinase-2
      cd14157
      Location:216 → 504
      STKc_IRAK2; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 2

    2. XM_015130249.2 → XP_014985735.2  interleukin-1 receptor-associated kinase-like 2 isoform X2

      UniProtKB/TrEMBL
      H9F3E8
      Conserved Domains (2) summary
      cd08795
      Location:3 → 91
      Death_IRAK2; Death domain of Interleukin 1 Receptor Associated Kinase-2
      cd14157
      Location:167 → 455
      STKc_IRAK2; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 2
    Nucleotide Protein
    Heading Accession and Version

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