BOK BCL2 family apoptosis regulator BOK [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: BOKprovided by VGNC
Official Full Name: BCL2 family apoptosis regulator BOKprovided by VGNC
Primary source: VGNC:VGNC:104511
See related: Ensembl:ENSMMUG00000056380
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	12	NC_041765.1 (129002737..129014011)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	12	NC_027904.1 (124430387..124441643)

Chromosome 12 - NC_041765.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D2S2142 (e-PCR)
- UniSTS:154274

G42020 (e-PCR)
- UniSTS:49343

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intrinsic apoptotic signaling pathway in response to DNA damage	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: bcl-2-related ovarian killer protein

Names: BOK, BCL2 family apoptosis regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001266922.1 → NP_001253851.1 bcl-2-related ovarian killer protein

See identical proteins and their annotated locations for NP_001253851.1

Status: PROVISIONAL

Source sequence(s)

JV048022

UniProtKB/TrEMBL

F6VX55, H9FYU9

Related

ENSMMUP00000064020.1, ENSMMUT00000100337.1

Conserved Domains (1) summary

cd06845
Location:37 → 177

Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...