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    ARHGEF5 Rho guanine nucleotide exchange factor 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705891, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGEF5provided by VGNC
    Official Full Name
    Rho guanine nucleotide exchange factor 5provided by VGNC
    Primary source
    VGNC:VGNC:80793
    See related
    Ensembl:ENSMMUG00000010134
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGEF5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (170735025..170760291)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (174855022..174880286, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114677064 Neighboring gene olfactory receptor 2A1/2A42-like Neighboring gene olfactory receptor, family 2, subfamily A, member 1 Neighboring gene NOBOX oogenesis homeobox Neighboring gene U6atac minor spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Rho guanine nucleotide exchange factor 5; rho guanine nucleotide exchange factor 5
    Names
    Rho guanine nucleotide exchange factor (GEF) 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      170735025..170760291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001094223.4 → XP_001094223.4  rho guanine nucleotide exchange factor 5

      UniProtKB/TrEMBL
      F6QYC0, G7MN79
      Related
      ENSMMUP00000013255.4, ENSMMUT00000014153.4
      Conserved Domains (5) summary
      cd11940
      Location:1514 → 1568
      SH3_ARHGEF5_19; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF5 and ARHGEF19
      PHA03247
      Location:497 → 970
      PHA03247; large tegument protein UL36; Provisional
      cd01221
      Location:1378 → 1504
      PH_ephexin; Ephexin Pleckstrin homology (PH) domain
      pfam00621
      Location:1178 → 1356
      RhoGEF; RhoGEF domain
      pfam15441
      Location:1 → 479
      ARHGEF5_35; Rho guanine nucleotide exchange factor 5/35
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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