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    SPHK2 sphingosine kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718088, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPHK2provided by VGNC
    Official Full Name
    sphingosine kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:77960
    Locus tag
    EGK_10845
    See related
    Ensembl:ENSMMUG00000022159
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPHK2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (48611761..48622585)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (43986554..43997297)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83 member E Neighboring gene sperm acrosome associated 4 Neighboring gene ribosomal protein L18 Neighboring gene D-box binding PAR bZIP transcription factor Neighboring gene carbonic anhydrase 11 Neighboring gene galactoside 2-alpha-L-fucosyltransferase 2-like Neighboring gene netrin 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables D-erythro-sphingosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphinganine-1-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingosine kinase 2
    NP_001244416.1
    XP_014979867.1
    XP_014979868.1
    XP_014979869.1
    XP_014979870.1
    XP_028694324.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257487.1 → NP_001244416.1  sphingosine kinase 2

      See identical proteins and their annotated locations for NP_001244416.1

      Status: PROVISIONAL

      Source sequence(s)
      JU335508
      UniProtKB/TrEMBL
      A0A8J8YL75, F6XJ72, F6ZFF5, G7NNQ6
      Related
      ENSMMUP00000031542.2, ENSMMUT00000038442.3
      Conserved Domains (1) summary
      pfam00781
      Location:186 → 320
      DAGK_cat; Diacylglycerol kinase catalytic domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      48611761..48622585
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838491.1 → XP_028694324.1  sphingosine kinase 2 isoform X1

      UniProtKB/TrEMBL
      F6XJ72, F6ZFC3
      Related
      ENSMMUP00000031544.3, ENSMMUT00000038444.3
      Conserved Domains (2) summary
      PLN02958
      Location:202 → 396
      PLN02958; diacylglycerol kinase/D-erythro-sphingosine kinase
      pfam15449
      Location:395 → 522
      Retinal; Retinal protein

    2. XM_015124382.2 → XP_014979868.1  sphingosine kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AND9, F6XJ72
      Conserved Domains (1) summary
      pfam00781
      Location:151 → 285
      DAGK_cat; Diacylglycerol kinase catalytic domain

    3. XM_015124381.2 → XP_014979867.1  sphingosine kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AND9, F6XJ72
      Conserved Domains (1) summary
      pfam00781
      Location:151 → 285
      DAGK_cat; Diacylglycerol kinase catalytic domain

    4. XM_015124384.2 → XP_014979870.1  sphingosine kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AND9, F6XJ72
      Related
      ENSMMUP00000078572.1, ENSMMUT00000092813.1
      Conserved Domains (1) summary
      pfam00781
      Location:151 → 285
      DAGK_cat; Diacylglycerol kinase catalytic domain

    5. XM_015124383.2 → XP_014979869.1  sphingosine kinase 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AND9, F6XJ72
      Related
      ENSMMUP00000029170.4, ENSMMUT00000031167.4
      Conserved Domains (1) summary
      pfam00781
      Location:151 → 285
      DAGK_cat; Diacylglycerol kinase catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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