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    RRM1 ribonucleotide reductase catalytic subunit M1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717990, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RRM1provided by VGNC
    Official Full Name
    ribonucleotide reductase catalytic subunit M1provided by VGNC
    Primary source
    VGNC:VGNC:76941
    Locus tag
    EGK_06625
    See related
    Ensembl:ENSMMUG00000003962
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RRM1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (64335041..64381508, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (63298766..63345242, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene RNA polymerase II subunit A C-terminal domain phosphatase SSU72 pseudogene Neighboring gene olfactory receptor 52B2-like Neighboring gene stromal interaction molecule 1 Neighboring gene non-histone chromosomal protein HMG-14 pseudogene Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in deoxyribonucleotide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ribonucleoside-diphosphate reductase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribonucleoside-diphosphate reductase large subunit
    Names
    ribonucleotide reductase M1 polypeptide
    NP_001252816.1
    XP_014970527.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265887.1 → NP_001252816.1  ribonucleoside-diphosphate reductase large subunit

      See identical proteins and their annotated locations for NP_001252816.1

      Status: PROVISIONAL

      Source sequence(s)
      JU476711
      UniProtKB/TrEMBL
      A0A1D5QBL6, A0A8J8YB73, F6Z9D7, G7NE70, H9FY72
      Related
      ENSMMUP00000005291.4, ENSMMUT00000005619.4
      Conserved Domains (3) summary
      cd01679
      Location:167 → 741
      RNR_I; Class I ribonucleotide reductase
      PLN02437
      Location:1 → 792
      PLN02437; ribonucleoside--diphosphate reductase large subunit
      pfam03477
      Location:1 → 89
      ATP-cone; ATP cone domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      64335041..64381508 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115041.2 → XP_014970527.1  ribonucleoside-diphosphate reductase large subunit isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZB27
      Conserved Domains (1) summary
      cl38938
      Location:1 → 695
      RNR_PFL; Ribonucleotide reductase and Pyruvate formate lyase
    Nucleotide Protein
    Heading Accession and Version

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