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    SPTBN2 spectrin beta, non-erythrocytic 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713419, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPTBN2provided by VGNC
    Official Full Name
    spectrin beta, non-erythrocytic 2provided by VGNC
    Primary source
    VGNC:VGNC:77872
    See related
    Ensembl:ENSMMUG00000020359
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPTBN2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (7820082..7865209)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (7691638..7736147)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene TOP6B like initiator of meiotic double strand breaks Neighboring gene ferritin light chain pseudogene Neighboring gene complement component 1 Q subcomponent-binding protein, mitochondrial pseudogene Neighboring gene RNA-binding protein 4B Neighboring gene RNA-binding protein 4 Neighboring gene RNA-binding protein 14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cortical actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of spectrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    spectrin beta chain, non-erythrocytic 2
    Names
    spectrin beta chain, brain 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      7820082..7865209
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015113614.2 → XP_014969100.2  spectrin beta chain, non-erythrocytic 2 isoform X2

      UniProtKB/TrEMBL
      A0A5K1UNR3, F6W8M4, H9FYV7
      Conserved Domains (4) summary
      smart00150
      Location:429 → 522
      SPEC; Spectrin repeats
      COG5069
      Location:51 → 441
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:1384 → 1588
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2221 → 2324
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain

    2. XM_015113615.2 → XP_014969101.2  spectrin beta chain, non-erythrocytic 2 isoform X2

      UniProtKB/TrEMBL
      A0A5K1UNR3, F6W8M4, H9FYV7
      Conserved Domains (4) summary
      smart00150
      Location:429 → 522
      SPEC; Spectrin repeats
      COG5069
      Location:51 → 441
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:1384 → 1588
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2221 → 2324
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain

    3. XM_015113617.2 → XP_014969103.2  spectrin beta chain, non-erythrocytic 2 isoform X2

      UniProtKB/TrEMBL
      A0A5K1UNR3, F6W8M4, H9FYV7
      Related
      ENSMMUP00000026792.4, ENSMMUT00000028635.4
      Conserved Domains (4) summary
      smart00150
      Location:429 → 522
      SPEC; Spectrin repeats
      COG5069
      Location:51 → 441
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:1384 → 1588
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2221 → 2324
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain

    4. XM_015113618.2 → XP_014969104.2  spectrin beta chain, non-erythrocytic 2 isoform X2

      UniProtKB/TrEMBL
      A0A5K1UNR3, F6W8M4, H9FYV7
      Conserved Domains (4) summary
      smart00150
      Location:429 → 522
      SPEC; Spectrin repeats
      COG5069
      Location:51 → 441
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:1384 → 1588
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2221 → 2324
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain

    5. XM_015113613.2 → XP_014969099.2  spectrin beta chain, non-erythrocytic 2 isoform X1

      UniProtKB/TrEMBL
      A0A5K1UNR3
      Conserved Domains (4) summary
      smart00150
      Location:436 → 529
      SPEC; Spectrin repeats
      COG5069
      Location:57 → 448
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:1391 → 1595
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      cd10571
      Location:2228 → 2331
      PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    Nucleotide Protein
    Heading Accession and Version

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